Evidence map›Paper›PMID 38649196›Full record

ArticleStroke and vascular neurology2025

VasCog Screen test: sensitive in detecting cognitive impairment in patients who had a stroke or with heart failure.

Nicole Yun Ching Chen, Melissa Yi Ling Tan, Jing Xu, Lijun Zuo, Yanhong Dong

Open access · goldAbstract readComparative Study
In one paragraph

Article in Stroke and vascular neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Nicole Yun Ching ChenYong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0003-3718-1127
Melissa Yi Ling TanDepartment of Medicine, National University of Singapore, Singapore.
Jing XuCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
Lijun ZuoDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China.ORCID 0000-0001-5565-8828
Yanhong DongAlice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore nurdy@nus.edu.sg.ORCID 0000-0002-3215-0164
National University of Singapore · SGCapital Medical University · CNDuke-NUS Medical School · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVascular diseases, such as stroke and heart failure (HF), are associated with cognitive decline. Vascular cognitive impairment (CI) is commonly found in patients who had a stroke and with HF, ranging from mild CI to dementia. Early detection of CI is crucial for effective management and rehabilitation. This study aimed to develop the VasCog Screen test, a screening tool to detect CI in patients who had a stroke and with HF.

method427 patients who had a stroke and with HF were assessed using cognitive measures including Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) and a formal neuropsychological battery. The short-MoCA was derived and combined with Symbol Digit Modalities Test (SDMT) to create the VasCog Screen. The discriminatory ability of different tests for CI was compared, establishing optimal cut-off points. Variants of short-MoCA including the SDMT were also evaluated.

resultsSimilar prevalence rates of CI were found in stroke and HF cohorts. The most prevalent neuropsychological impairment was visuomotor speed, followed by visual memory and visuoconstruction. More than half of the patients were found to have CI. The VasCog Screen outperformed MMSE, MoCA and short-MoCA in detecting CI. The addition of SDMT to variants of the short-MoCA increased diagnostic accuracy.

conclusionThe VasCog Screen test offers a cognitive screening tool, which is sensitive to cognitive deficits characteristically found in patients who had a stroke and with HF. It was found to have good sensitivity, specificity and classification accuracy. It is easy to administer in busy clinics, enabling early detection of CI and facilitating appropriate interventions.

Indexed as

CognitionCognitive DysfunctionHeart FailureMental Status and Dementia TestsNeuropsychological TestsStrokeAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsPrevalenceReproducibility of ResultsRisk FactorsBrainCerebrovascular DisordersCognitive DysfunctionStroke

Identifiers

PMID38649196
PMCPMC11877426
OpenAlexW4394996771

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.