Evidence map›Paper›PMID 38649749›Full record

ArticleClinical and translational medicine2024

Synergistic inhibition of progesterone receptor-A/B signalling by simvastatin and mifepristone in human uterine leiomyomas.

Sadia Afrin, Gregory W Kirschen, Mariko Miyashita-Ishiwata, Malak El Sabeh, Mostafa A Borahay

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sadia AfrinDepartment of Gynecology and Obstetrics, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
Gregory W KirschenDepartment of Gynecology and Obstetrics, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
Mariko Miyashita-IshiwataDepartment of Gynecology and Obstetrics, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
Malak El SabehDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA.
Mostafa A BorahayDepartment of Gynecology and Obstetrics, The Johns Hopkins Hospital, Baltimore, Maryland, USA.ORCID 0000-0002-0554-132X
Johns Hopkins Hospital · USBaylor College of Medicine · US

Funding

Mechanisms of actions(s) of simvastatin in uterine leiomyomaR01HD094380 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BORAHAY, MOSTAFA A. · 2018 to 2022
$4.0M
NICHD NIH HHS R01 HD094380NIH HHS R01HD094380
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LeiomyomaMifepristoneReceptors, ProgesteroneSignal TransductionSimvastatinDrug SynergismFemaleHumansUterine NeoplasmsMifepristoneReceptors, ProgesteroneSimvastatin

Identifiers

PMID38649749
PMCPMC11035378
OpenAlexW4395046543

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.