Evidence mapPaperPMID 38650100Full record

ReviewDiabetes & metabolism journal2024

Glucagon-Like Peptide-1: New Regulator in Lipid Metabolism.

Tong Bu, Ziyan Sun, Yi Pan, Xia Deng, Guoyue Yuan

Open access · goldAbstract readReview
In one paragraph

Review in Diabetes & metabolism journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
29.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Peptide-functionalized nanoemulsions with exendin-4 as a model ligand.International journal of pharmaceutics: X · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Efficacy and safety of glucagon-like peptide-1 (GLP-1) agonists in pediatric obesity: A systematic review and meta-analysis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Metabolites · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Females are protected from semaglutide-induced muscle loss inbioRxiv : the preprint server for biology · 2026
    Article
  18. Review
  19. Review
  20. Improving Lipid Profiles ThroughFoods (Basel, Switzerland) · 2026
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tong BuDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Ziyan SunDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Yi PanDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Xia DengDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Guoyue YuanDepartment of Endocrinology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Jiangsu University · CN

Funding

Hospital of Jiangsu University BGYCB202206Hospital of Jiangsu University jdfykc2021005Key R&D Plan Social Development Project of Jiangsu Province SBE2023741128National Natural Science Foundation of China 82300903National Natural Science Foundationof Jiangsu Province SBK2023022865Projects from Social Development of Zhenjiang SH2023029sixth phase 333 second level talent training project of Jiangsu Province BRA2022008Youth Science and Technology Talent Recruitment Project of Zhenjiang city ZJTJ2101
6 · The paper itself

Abstract

Glucagon-like peptide-1 (GLP-1) is a 30-amino acid peptide hormone that is mainly expressed in the intestine and hypothalamus. In recent years, basic and clinical studies have shown that GLP-1 is closely related to lipid metabolism, and it can participate in lipid metabolism by inhibiting fat synthesis, promoting fat differentiation, enhancing cholesterol metabolism, and promoting adipose browning. GLP-1 plays a key role in the occurrence and development of metabolic diseases such as obesity, nonalcoholic fatty liver disease, and atherosclerosis by regulating lipid metabolism. It is expected to become a new target for the treatment of metabolic disorders. The effects of GLP-1 and dual agonists on lipid metabolism also provide a more complete treatment plan for metabolic diseases. This article reviews the recent research progress of GLP-1 in lipid metabolism.

Indexed as

Glucagon-Like Peptide 1Lipid MetabolismObesityAdipose TissueAnimalsAtherosclerosisHumansNon-alcoholic Fatty Liver DiseaseGlucagon-Like Peptide 1Adipose tissueGlucagon-like peptide 1Lipid metabolismNon-alcoholic fatty liver diseaseObesity

Identifiers

PMID38650100
PMCPMC11140404
OpenAlexW4393581969

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.