Evidence map›Paper›PMID 38654828›Full record

ArticleElectrochimica acta2024

Measurement of Neuropeptide Y in Aptamer-Modified Planar Electrodes.

Luis López, Lyza M Martínez, Jaileen R Caicedo, Lauren Fernández-Vega, Lisandro Cunci

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Electrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Luis LópezDepartment of Chemistry, University of Puerto Rico - Rio Piedras, 17 Ave Universidad Ste 1701, San Juan, Puerto Rico 00931, United States.
Lyza M MartínezDepartment of Chemistry, Universidad Ana G. Méndez - Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Jaileen R CaicedoDepartment of Chemistry, University of Puerto Rico - Rio Piedras, 17 Ave Universidad Ste 1701, San Juan, Puerto Rico 00931, United States.
Lauren Fernández-VegaDepartment of Chemistry, Universidad Ana G. Méndez - Gurabo, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Lisandro CunciDepartment of Chemistry, University of Puerto Rico - Rio Piedras, 17 Ave Universidad Ste 1701, San Juan, Puerto Rico 00931, United States.
University of Puerto Rico at Río Piedras · PRAna G. Mendez University System · PR

Funding

Development and Validation of an NPY-sensitive Microelectrode for Measuring NPY Release from HippocampusR21MH129037 · NIMH · UNIVERSITY COLLEGE OF TURABO (CAGUAS,PR) · PI CUNCI, LISANDRO, DOBRUNZ, LYNN E · 2021 to 2022
$382k
NIMH NIH HHS R21 MH129037
6 · The paper itself

Abstract

Electrochemical impedance spectroscopy (EIS) is a powerful technique for studying the interaction at electrode/solution interfaces. The adoption of EIS for obtaining analytical signals in biosensors based on aptamers is gaining popularity because of its advantageous characteristics for molecular recognition. Neuropeptide Y (NPY), the most abundant neuropeptide in the body, plays a crucial role with its stress-relieving properties. Quantitative measurement of NPY is imperative for understanding its role in these and other biological processes. Although aptamer-modified electrodes for NPY detection using EIS present a promising alternative, the correlation between the data obtained and the adsorption process on the electrodes is not fully understood. Various studies utilize the change in charge transfer resistance when employing an active redox label. In contrast, label-free measurement relies on changes in capacitance. To address these challenges, we focused on the interaction between aptamer-modified planar electrodes and their target, NPY. We proposed utilizing -ω*Z

Indexed as

BiosensingElectrochemical impedance spectroscopyLangmuir isothermNeuropeptide YSingle layer adsorption

Identifiers

PMID38654828
PMCPMC11034791
OpenAlexW4394618998

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.