Evidence mapPaperPMID 38656371Full record

ArticleDiabetologia2024

Associations of 24 h time-use compositions of sitting, standing, physical activity and sleeping with optimal cardiometabolic risk and glycaemic control: The Maastricht Study.

Christian J Brakenridge, Annemarie Koster, Bastiaan E de Galan, Alison Carver, Dorothea Dumuid, Francis Q S Dzakpasu, Simone J P M Eussen, Hans H C M Savelberg, Hans Bosma, Neville Owen and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Diabetologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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  18. Associations of neighbourhood walkability with patterns of device-measured stepping, standing and sitting.The international journal of behavioral nutrition and physical activity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Christian J BrakenridgeBaker Heart and Diabetes Institute, Melbourne, VIC, Australia. cbrakenridge@swin.edu.au.ORCID http://orcid.org/0000-0001-6022-7539
Annemarie KosterDepartment of Social Medicine, Maastricht University, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0003-1583-7391
Bastiaan E de GalanDepartment of Internal Medicine, Maastricht University Medical Center+, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0002-1255-7741
Alison CarverNational Centre for Healthy Ageing, The School of Translational Medicine, Monash University, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0001-5166-3574
Dorothea DumuidAlliance for Research in Exercise, Nutrition and Activity, University of South Australia, Adelaide, SA, Australia.ORCID http://orcid.org/0000-0003-3057-0963
Francis Q S DzakpasuBaker Heart and Diabetes Institute, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0002-5536-0199
Simone J P M EussenCAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0003-0559-6838
Hans H C M SavelbergDepartment of Nutrition and Movement Science, Maastricht University, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0002-8864-2109
Hans BosmaDepartment of Social Medicine, Maastricht University, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0003-4333-4564
Neville OwenBaker Heart and Diabetes Institute, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0003-2784-4820
Nicolaas C SchaperCAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands.ORCID http://orcid.org/0000-0002-2128-8029
Genevieve N HealySchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD, Australia.ORCID http://orcid.org/0000-0001-7093-7892
David W DunstanBaker Heart and Diabetes Institute, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0003-2629-9568
Maastricht University · NLBaker Heart and Diabetes Institute · AUDepartment of Health and Aged Care · AURadboud University Nijmegen · NLThe University of Queensland · AUUniversity of South Australia · AU

Funding

Australian Research Council DE230101174National Health and Medical Research Council Fellowships schemeNational Health and Medical Research Council MRFF Emerging Leadership Investigator Grant (#1193
6 · The paper itself

Abstract

aims/hypothesisThe associations of sitting, standing, physical activity and sleep with cardiometabolic health and glycaemic control markers are interrelated. We aimed to identify 24 h time-use compositions associated with optimal metabolic and glycaemic control and determine whether these varied by diabetes status.

methodsThigh-worn activPAL data from 2388 participants aged 40-75 years (48.7% female; mean age 60.1 [SD = 8.1] years; n=684 with type 2 diabetes) in The Maastricht Study were examined. Compositional isometric log ratios were generated from mean 24 h time use (sitting, standing, light-intensity physical activity [LPA], moderate-to-vigorous physical activity [MVPA] and sleeping) and regressed with outcomes of waist circumference, fasting plasma glucose (FPG), 2 h plasma glucose, HbA

resultsCompositions lower in sitting time and with greater standing time, physical activity and sleeping had the most beneficial associations with outcomes. Associations were stronger in participants with type 2 diabetes (p<0.05 for interactions), with larger estimated benefits for waist circumference, FPG and HbA CONCLUSIONS/

interpretationShorter sitting time and more time spent standing, undergoing physical activity and sleeping are associated with preferable cardiometabolic health. The substitutions of behavioural time use were significantly stronger in their associations with glycaemic control in those with type 2 diabetes compared with those with normoglycaemic metabolism, especially when sitting time was balanced with greater physical activity.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2ExerciseGlycemic ControlSitting PositionSleepAdultAgedCardiometabolic Risk FactorsCross-Sectional StudiesFemaleGlycated HemoglobinHumansMaleMiddle AgedSedentary BehaviorBlood GlucoseGlycated HemoglobinCardiometabolic riskGlycaemic controlPhysical activitySittingSleepTime use

Identifiers

PMID38656371
PMCPMC11153304
OpenAlexW4395074229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.