Evidence map›Paper›PMID 38656877›Full record

ArticleAging2024

Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients.

Henry Raab, Elizabeth R Hauser, Lydia Coulter Kwee, Svati H Shah, William E Kraus, Cavin K Ward-Caviness

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Henry RaabCenter for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC 27514, USA.
Elizabeth R HauserDuke University Molecular Physiology Institute, Duke University, Durham, NC 27701, USA.
Lydia Coulter KweeDuke University Molecular Physiology Institute, Duke University, Durham, NC 27701, USA.
Svati H ShahDuke University Molecular Physiology Institute, Duke University, Durham, NC 27701, USA.
William E KrausDuke University Molecular Physiology Institute, Duke University, Durham, NC 27701, USA.
Cavin K Ward-CavinessCenter for Public Health and Environmental Assessment, US Environmental Protection Agency, Chapel Hill, NC 27514, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research into aging has grown substantially with the creation of molecular biomarkers of biological age that can be used to determine age acceleration. Concurrently, nuclear magnetic resonance (NMR) assessment of biomarkers of inflammation and metabolism provides researchers with new ways to examine intermediate risk factors for chronic disease. We used data from a cardiac catheterization cohort to examine associations between biomarkers of cardiometabolic health and accelerated aging assessed using both gene expression (Transcriptomic Age) and DNA methylation (Hannum Age, GrimAge, Horvath Age, and Phenotypic Age). Linear regression models were used to associate accelerated aging with each outcome (cardiometabolic health biomarkers) while adjusting for chronological age, sex, race, and neighborhood socioeconomic status. Our study shows a robust association between GlycA and GrimAge (5.71, 95% CI = 4.36, 7.05,

Indexed as

AgingBiomarkersCardiac CatheterizationInflammationMagnetic Resonance SpectroscopyAgedDNA MethylationFemaleHumansMaleMiddle AgedBiomarkersbiological agingbiomarkerscardiac catheterizationNMR

Identifiers

PMID38656877
PMCPMC11087135

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.