Evidence map›Paper›PMID 38657993›Full record

ArticleSaudi medical journal2024

The immunologic abnormalities in patients with paroxysmal nocturnal hemoglobinuria are associated with disease progression.

Guanrou Wang, Mengting Che, Lijie Zeng, Hui Liu, Liyan Li, Zhaoyun Liu, Rong Fu

Open access · diamondAbstract read
In one paragraph

Article in Saudi medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Free GPIs and Comparison of GPI Structures Among Species.International journal of molecular sciences · 2025
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Guanrou WangFrom the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Mengting CheFrom the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Lijie ZengFrom the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Hui Liu
Liyan Li
Zhaoyun LiuFrom the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Rong FuFrom the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.ORCID https://orcid.org/0000-0002-9928-9224
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo suggest the presence of a hyperimmune state in patients, and indicate that immune system attack on glycosylphosphatidylinositol (+) (GPI

methodsWe retrospective the immune cell subtypes in peripheral blood from 25 patients visiting Tianjin Medical University General Hospital, Tianjin, China, with classical paroxysmal nocturnal hemoglobinuria (PNH) and 50 healthy controls.

resultsThe total CD3

conclusionOur results demonstrated that immune abnormalities are associated with PNH development.

Indexed as

Disease ProgressionHemoglobinuria, ParoxysmalAdultAntigens, CD19Case-Control StudiesCD3 ComplexDendritic CellsFemaleGlycosylphosphatidylinositolsHumansL-Lactate DehydrogenaseMaleMiddle AgedMonocytesRetrospective StudiesYoung AdultAntigens, CD19CD3 ComplexGlycosylphosphatidylinositolsL-Lactate DehydrogenaseB-cellscytokinesdendritic cellsparoxysmal nocturnal hemoglobinuriaT-cells

Identifiers

PMID38657993
PMCPMC11147583
OpenAlexW4395077036

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.