Evidence map›Paper›PMID 38664120›Full record

ReviewSeminars in cell & developmental biology

Out with the old, in with the new: Meiotic driving of sex chromosome evolution.

Callie M Swanepoel, Jacob L Mueller

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Signatures of sex ratio distortion in humans.bioRxiv : the preprint server for biology · 2026
    Article
  2. The evolutionary genomics of meiotic drive.Molecular biology and evolution · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Callie M SwanepoelDepartment of Human Genetics, University of Michigan Medical School, 1241 E. Catherine St, Ann Arbor, MI, USA.
Jacob L MuellerDepartment of Human Genetics, University of Michigan Medical School, 1241 E. Catherine St, Ann Arbor, MI, USA. Electronic address: jacobmu@umich.edu.
University of Michigan–Ann Arbor · US

Funding

PREDOCTORAL TRAINING IN GENETICST32GM007544 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORAN, JOHN V. · 1985 to 2022
$11.3M
Career Training in Reproductive BiologyT32HD079342 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Suzanne M MOENTER · 2014 to 2026
$2.3M
Roles of X- and Y-palindromic Genes in Mammalian FertilityR01HD094736 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MUELLER, JACOB L · 2018 to 2022
$1.8M
Tracking the Rapid Evolution of Sex Chromosome Palindromes and Their GenesF31HD104339 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SWANEPOEL, CALLIE · 2021 to 2023
$127k
NICHD NIH HHS F31 HD104339NICHD NIH HHS R01 HD094736NICHD NIH HHS T32 HD079342NIGMS NIH HHS T32 GM007544
6 · The paper itself

Abstract

Chromosomal regions with meiotic drivers exhibit biased transmission (> 50 %) over their competing homologous chromosomal region. These regions often have two prominent genetic features: suppressed meiotic crossing over and rapidly evolving multicopy gene families. Heteromorphic sex chromosomes (e.g., XY) often share these two genetic features with chromosomal regions exhibiting meiotic drive. Here, we discuss parallels between meiotic drive and sex chromosome evolution, how the divergence of heteromorphic sex chromosomes can be influenced by meiotic drive, experimental approaches to study meiotic drive on sex chromosomes, and meiotic drive in traditional and non-traditional model organisms with high-quality genome assemblies. The newly available diversity of high-quality sex chromosome sequences allows us to revisit conventional models of sex chromosome evolution through the lens of meiotic drive.

Indexed as

Evolution, MolecularMeiosisSex ChromosomesAnimalsHumansEvolutionMeiotic driveMulticopy genesSex chromosomesSuppressed recombination

Identifiers

PMID38664120
PMCPMC11351068
OpenAlexW4395068266

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.