Evidence map›Paper›PMID 38664370›Full record

ReviewCell death discovery2024

Emerging roles of circular RNAs in nasopharyngeal carcinoma: functions and implications.

Aiyu Ma, Yuzhong Yang, Lu Lu, Yan Zhang, Xuemei Zhang, Jinhua Zheng, Xiang Zheng

Open access · goldAbstract readReview
In one paragraph

Review in Cell death discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aiyu Ma *Department of Pathology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.ORCID http://orcid.org/0009-0006-0631-3544
Yuzhong Yang *Department of Pathology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.
Lu LuDepartment of Pathology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.ORCID http://orcid.org/0009-0009-0367-9446
Yan ZhangDepartment of Pathology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.ORCID http://orcid.org/0000-0002-0255-7799
Xuemei ZhangDepartment of Pathology, Liuzhou People's Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi, China.
Jinhua ZhengDepartment of Pathology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China. 513932237@qq.com.ORCID http://orcid.org/0009-0000-0666-0868
Xiang ZhengDepartment of Pathology, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China. xiangzheng12@sina.com.ORCID http://orcid.org/0009-0007-3048-7015
Guilin Medical University · CNFourth Affiliated Hospital of Guangxi Medical University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82060042Natural Science Foundation of Guangxi Zhuang Autonomous Region 2020GXNSFBA297082Scientific Research and Technology Development Program of Guangxi (Guangxi Scientific Research and Technology Development Program) AD23026251
6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is a distinct malignancy primarily prevalent in Southern China and Southeast Asia. Circular RNAs (circRNAs), a class of non-coding RNAs, are evolutionarily conserved and exhibit remarkable stability. Their dysregulation has been observed in various cancers, including NPC. In this review, we investigate the pivotal role of circRNAs in NPC, focusing specifically on their involvement in tumor proliferation, apoptosis, metastasis, angiogenesis, stemness, metabolism, and the tumor microenvironment. We highlight the diagnostic and prognostic potential of circRNAs in NPC, emphasizing their utility as biomarkers for early detection, disease monitoring, and prediction of treatment outcomes. Additionally, we explore the therapeutic implications of circRNAs in NPC, highlighting their potential for targeted therapies.

Identifiers

PMID38664370
PMCPMC11045839
OpenAlexW4395450468

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.