Evidence map›Paper›PMID 38664778›Full record

ReviewJournal of nanobiotechnology2024

The potential use of nanozymes as an antibacterial agents in oral infection, periodontitis, and peri-implantitis.

Mohammad Hosseini Hooshiar, Ashkan Badkoobeh, Shirin Kolahdouz, Azadeh Tadayonfard, Asieh Mozaffari, Kamyar Nasiri, Sara Salari, Reza Safaralizadeh, Saman Yasamineh

Expression of concernOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
8.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Mohammad Hosseini HooshiarDepartment of Periodontology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Ashkan BadkoobehDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.
Shirin KolahdouzSchool of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Azadeh TadayonfardPostgraduate Department of Prosthodontics, Dental Faculty, Tehran University of Medical Sciences, Tehran, Iran.
Asieh MozaffariDepartment of Periodontics, Faculty of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.
Kamyar NasiriDepartment of Dentistry, Islamic Azad University of Medical Sciences, Tehran, Iran.
Sara SalariIslamic Azad University of Medical Sciences, Esfahan, Iran.
Reza SafaralizadehRestarative Dentistry, Department of Dental, Faculty Tabriz Medical University, Tabriz, Iran. rezasafaralizadeh@yahoo.com.
Saman YasaminehYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran. Yassaman124@gmail.com.
Tehran University of Medical Sciences · IRIslamic Azad University, Isfahan · IRIslamic Azad University Medical Branch of Tehran · IRIslamic Azad University of Tabriz · IRQazvin University of Medical Sciences · IRQom University of Medical Science and Health Services · IRShahid Sadoughi University of Medical Sciences and Health Services · IRTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies suggest that oral pathogenic biofilms cause persistent oral infections. Among these is periodontitis, a prevalent condition brought on by plaque biofilm. It can even result in tooth loss. Furthermore, the accumulation of germs around a dental implant may lead to peri-implantitis, which damages the surrounding bone and gum tissue. Furthermore, bacterial biofilm contamination on the implant causes soft tissue irritation and adjacent bone resorption, severely compromising dental health. On decontaminated implant surfaces, however, re-osseointegration cannot be induced by standard biofilm removal techniques such as mechanical cleaning and antiseptic treatment. A family of nanoparticles known as nanozymes (NZs) comprise highly catalytically active multivalent metal components. The most often employed NZs with antibacterial activity are those that have peroxidase (POD) activity, among other types of NZs. Since NZs are less expensive, more easily produced, and more stable than natural enzymes, they hold great promise for use in various applications, including treating microbial infections. NZs have significantly contributed to studying implant success rates and periodontal health maintenance in periodontics and implantology. An extensive analysis of the research on various NZs and their applications in managing oral health conditions, including dental caries, dental pulp disorders, oral ulcers, peri-implantitis, and bacterial infections of the mouth. To combat bacteria, this review concentrates on NZs that imitate the activity of enzymes in implantology and periodontology. With a view to the future, there are several ways that NZs might be used to treat dental disorders antibacterially.

Indexed as

Anti-Bacterial AgentsBiofilmsDental ImplantsPeri-ImplantitisPeriodontitisAnimalsBacteriaHumansNanoparticlesAnti-Bacterial AgentsDental ImplantsAntibacterialNanozymesOral infectionPeri-implantitisPeriodontitis

Identifiers

PMID38664778
PMCPMC11044492
OpenAlexW4395453834

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.