Evidence map›Paper›PMID 38665661›Full record

ArticleJACS Au2024

Taming Conformational Heterogeneity on Ion Racetrack to Unveil Principles that Drive Membrane Permeation of Cyclosporines.

Miranda N Limbach, Edward T Lindberg, Hernando J Olivos, Lara van Tetering, Carlos A Steren, Jonathan Martens, Van A Ngo, Jos Oomens, Thanh D Do

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miranda N LimbachDepartment of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.ORCID https://orcid.org/0000-0003-4266-7279
Edward T LindbergDepartment of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.
Hernando J OlivosWaters Corporation, Milford, Massachusetts 01757, United States.
Lara van TeteringInstitute for Molecules and Materials, FELIX Laboratory, Radboud University, Toernooiveld 7, Nijmegen 6525 ED, The Netherlands.ORCID https://orcid.org/0009-0003-5070-6116
Carlos A SterenDepartment of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.ORCID https://orcid.org/0000-0002-0455-4137
Jonathan MartensInstitute for Molecules and Materials, FELIX Laboratory, Radboud University, Toernooiveld 7, Nijmegen 6525 ED, The Netherlands.ORCID https://orcid.org/0000-0001-9537-4117
Van A NgoAdvanced Computing for Life Sciences and Engineering Group, Science Engagement Section, National Center for Computational Sciences, Computing and Computational Sciences Directorate, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, United States.ORCID https://orcid.org/0000-0001-8350-1203
Jos OomensInstitute for Molecules and Materials, FELIX Laboratory, Radboud University, Toernooiveld 7, Nijmegen 6525 ED, The Netherlands.
Thanh D DoDepartment of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.ORCID https://orcid.org/0000-0002-1978-4365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study reveals the underlying principles governing the passive membrane permeability in three large

Identifiers

PMID38665661
PMCPMC11040698

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.