Evidence map›Paper›PMID 38665997›Full record

ArticleMedComm2024

Mineral crude drug mirabilite (Mangxiao) inhibits the occurrence of colorectal cancer by regulating the

Xiaohang Zhou, Hui Sun, Junling Ren, Guangli Yan, Le Yang, Honglian Zhang, Haitao Lu, Xinghua Li, Toshiaki Makino, Fengting Yin and 2 more

Open access · goldAbstract read
In one paragraph

Article in MedComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Xiaohang ZhouState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Hui SunState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Junling RenState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Guangli YanState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Le YangState Key Laboratory of Dampness Syndrome The Second Affiliated Hospital Guangzhou University of Chinese Medicine Guangzhou China.
Honglian ZhangDepartment of Traditional Chinese Medicine, Pharmacy College Qiqihar Medical University Qiqihar China.
Haitao LuHong Kong Traditional Chinese Medicine Phenome Research Centre, School of Chinese Medicine Hong Kong Baptist University Hong Kong China.
Xinghua LiState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Toshiaki MakinoDepartment of Pharmacognosy Graduate School of Pharmaceutical Sciences Nagoya City University Nagoya Japan.
Fengting YinState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Jing LiState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Xijun WangState Key Laboratory of Integration and Innovation of Classical Formula and Modern Chinese Medicine National Chinmedomics Research Center National TCM Key Laboratory of Serum Pharmacochemistry Metabolomics Laboratory Department of Pharmaceutical Analysis Heilongjiang University of Chinese Medicine Harbin China.
Heilongjiang University of Chinese Medicine · CNGuangzhou University of Chinese Medicine · CNHong Kong Baptist University · HKNagoya City University · JPQiqihar Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mineral crude drug has revolutionized the treatment landscape in precision oncology niche that leads to the improvement in therapeutic efficiency on various tumor subtypes. Mangxiao (MX), a mineral crude drug in traditional Chinese medicine, has been used for treating gastrointestinal diseases for thousands of years. However, the action mechanisms are still ambiguous. Here, we attempt to explore inhibitory roles and associated pharmacological mechanisms of MX upon colorectal cancer (CRC) in APC

Indexed as

colorectal cancerMangxiaomultiomicstraditional Chinese medicine

Identifiers

PMID38665997
PMCPMC11043829
OpenAlexW4395463255

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.