Evidence map›Paper›PMID 38667166›Full record

ArticleBiosensors2024

Detection of NT-proBNP Using Optical Fiber Back-Reflection Plasmonic Biosensors.

Ana Sofia Assunção, Miguel Vidal, Maria João Martins, Ana Violeta Girão, Médéric Loyez, Christophe Caucheteur, José Mesquita-Bastos, Florinda M Costa, Sónia O Pereira, Cátia Leitão

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ana Sofia Assunçãoi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4102-0310
Miguel Vidali3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-5890-2566
Maria João Martinsi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.
Ana Violeta GirãoCICECO-Aveiro Institute of Materials, Department of Materials and Ceramics Engineering, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-2699-646X
Médéric LoyezElectromagnetism and Telecommunication Department, University of Mons, 31 Bld Dolez, 7000 Mons, Belgium.ORCID 0000-0001-8858-7413
Christophe CaucheteurElectromagnetism and Telecommunication Department, University of Mons, 31 Bld Dolez, 7000 Mons, Belgium.
José Mesquita-BastosInstitute of Biomedicine-iBiMED, School of Health Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-9526-3123
Florinda M Costai3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-8729-714X
Sónia O Pereirai3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4174-7253
Cátia Leitãoi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-6331-1215
University of Aveiro · PTUniversity of Mons · BE

Funding

Fundação para a Ciência e Tecnologia CEECIND/00154/2020Fundação para a Ciência e Tecnologia LA/P/0037/2020, UIDB/50025/2020 & UIDP/50025/2020
6 · The paper itself

Abstract

Heart failure (HF) is a clinical entity included in cardiovascular diseases affecting millions of people worldwide, being a leading cause of hospitalization of older adults, and therefore imposing a substantial economic burden on healthcare systems. HF is characterized by dyspnea, fatigue, and edema associated with elevated blood levels of natriuretic peptides, such as N Terminal pro-B-type Natriuretic Peptide (NT-proBNP), for which there is a high demand for point of care testing (POCT) devices. Optical fiber (OF) biosensors offer a promising solution, capable of real-time detection, quantification, and monitoring of NT-proBNP concentrations in serum, saliva, or urine. In this study, immunosensors based on plasmonic uncladded OF tips were developed using OF with different core diameters (200 and 600 µm). The tips were characterized to bulk refractive index (RI), anddetection tests were conducted with NT-proBNP concentrations varying from 0.01 to 100 ng/mL. The 200 µm sensors showed an average total variation of 3.6 ± 2.5 mRIU, an average sensitivity of 50.5 mRIU/ng·mL

Indexed as

Biosensing TechniquesNatriuretic Peptide, BrainOptical FibersPeptide FragmentsHeart FailureHumansLimit of DetectionNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)gold plasmonicsN-terminal B-type natriuretic peptide (NT-proBNP)optical fiber uncladded tip biosensorssurface plasmon resonance (SPR)

Identifiers

PMID38667166
PMCPMC11048293
OpenAlexW4393950577

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.