Evidence map›Paper›PMID 38667586›Full record

ArticleHealthcare (Basel, Switzerland)2024

Blood Cell Ratios Unveiled: Predictive Markers of Myocardial Infarction Prognosis.

Cosmina Elena Jercălău, Cătălina Liliana Andrei, Roxana Oana Darabont, Suzana Guberna, Arina Maria Staicu, Cătălin Teodor Rusu, Octavian Ceban, Crina Julieta Sinescu

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. International journal of general medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cosmina Elena JercălăuDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.ORCID 0000-0003-3290-2730
Cătălina Liliana AndreiDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.
Roxana Oana DarabontDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.
Suzana GubernaDepartment of Cardiology, Emergency Hospital "Bagdasar-Arseni", 050474 Bucharest, Romania.
Arina Maria StaicuDepartment of Cardiology, Emergency Hospital "Bagdasar-Arseni", 050474 Bucharest, Romania.
Cătălin Teodor RusuDepartment of Internal Medicine, "Coltea" Clinical Hospital, 030167 Bucharest, Romania.
Octavian CebanEconomic Cybernetics and Informatics Department, The Bucharest University of Economic Studies, 010374 Bucharest, Romania.ORCID 0000-0003-3439-3247
Crina Julieta SinescuDepartment of Cardiology, "Bagdasar Arseni" Emergency Hospital, University of Medicine and Pharmacy "Carol Davila", 011241 Bucharest, Romania.ORCID 0000-0001-5933-8549
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROBucharest University of Economic Studies · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEven if the management and treatment of patients with non-ST-elevation myocardial infarction (NSTEMI) have significantly evolved, it is still a burgeoning disease, an active volcano with very high rates of morbidity and mortality. Therefore, novel management and therapeutic strategies for this condition are urgently needed. Lately, theories related to the role of various blood cells in NSTEMI have emerged, with most of this research having so far been focused on correlating the ratios between various leukocyte types (neutrophil/lymphocyte ratio-NLR, neutrophil/monocyte ratio-NMR). But what about erythrocytes? Is there an interaction between these cells and leukocytes, and furthermore, can this relationship influence NSTEMI prognosis? Are they partners in crime?

methodsThrough the present study, we sought, over a period of sixteen months, to evaluate the neutrophil/red blood cell ratio (NRR), monocyte/red blood cell ratio (MRR) and lymphocyte/red blood cell ratio (LRR), assessing their potential role as novel prognostic markers in patients with NSTEMI.

resultsThere was a statistically significant correlation between the NRR, LRR, MRR and the prognosis of NSTEMI patients.

conclusionsThese new predictive markers could represent the start of future innovative therapies that may influence crosstalk pathways and have greater benefits in terms of cardiac repair and the secondary prevention of NSTEMI.

Indexed as

biomarkercardiovascular diseaseprognosisrisk stratificationtherapy

Identifiers

PMID38667586
PMCPMC11049867
OpenAlexW4394856185

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.