Evidence map›Paper›PMID 38670050›Full record

ArticleBrain and cognition2024

Frontoparietal beta event characteristics are associated with early life stress and psychiatric symptoms in adults.

Brian C Kavanaugh, Megan M Vigne, Eric Tirrell, W Luke Acuff, Andrew M Fukuda, Ryan Thorpe, Anna Sherman, Stephanie R Jones, Linda L Carpenter, Audrey R Tyrka

Open access · greenAbstract read
In one paragraph

Article in Brain and cognition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Brian C KavanaughE.P. Bradley Hospital, Riverside RI, USA, Brown University; Department of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA. Electronic address: Brian_Kavanaugh@Brown.edu.
Megan M VigneDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA; Butler Hospital COBRE Center for Neuromodulation, Providence RI, USA.
Eric TirrellDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA; Butler Hospital COBRE Center for Neuromodulation, Providence RI, USA.
W Luke AcuffDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA; Butler Hospital COBRE Center for Neuromodulation, Providence RI, USA.
Andrew M FukudaDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA; Butler Hospital COBRE Center for Neuromodulation, Providence RI, USA.
Ryan ThorpeBrown University, Department of Neuroscience, Providence RI, USA , Providence Veteran's Association Medical Center.
Anna ShermanDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA; Butler Hospital COBRE Center for Neuromodulation, Providence RI, USA.
Stephanie R JonesBrown University, Department of Neuroscience, Providence RI, USA , Providence Veteran's Association Medical Center; Center for Neurorestoration and Neurotechnology, Providence RI, USA.
Linda L CarpenterDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA; Butler Hospital COBRE Center for Neuromodulation, Providence RI, USA.
Audrey R TyrkaDepartment of Psychiatry & Human Behavior, Alpert Medical School of Brown University, Providence RI, USA; Butler Hospital COBRE Center for Neuromodulation, Providence RI, USA.
Butler Hospital · USProvidence VA Medical Center · USBradley Hospital · US

Funding

Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI KayLoni L. Olson · 2021 to 2026
$14.6M
Neuroimaging and Neuromodulation CoreP20GM130452 · NIGMS · BUTLER HOSPITAL (PROVIDENCE, RI) · PI MCLAUGHLIN, NICOLE CR · 2019 to 2023
$11.3M
Early Life Stress: Epigenetic Regulation of Endocrine and Immune PathwaysR01MH101107 · NIMH · BUTLER HOSPITAL (PROVIDENCE, RI) · PI TYRKA, AUDREY · 2014 to 2018
$2.6M
Training Program for Interactionist Cognitive Neuroscience (ICoN)T32MH115895 · NIMH · BROWN UNIVERSITY · PI MICHAEL J. FRANK, STEPHANIE Ruggiano JONES · 2019 to 2026
$1.8M
Modulation of Frontoparietal Dynamics in Adolescent Working Memory DeficitsK23MH129853 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI Brian Kavanaugh · 2022 to 2026
$920k
NIGMS NIH HHS P20 GM130452NIGMS NIH HHS P20 GM139767NIMH NIH HHS K23 MH129853NIMH NIH HHS R01 MH101107NIMH NIH HHS T32 MH115895
6 · The paper itself

Abstract

Recent work has found that the presence of transient, oscillatory burst-like events, particularly within the beta band (15-29 Hz), is more closely tied to disease state and behavior across species than traditional electroencephalography (EEG) power metrics. This study sought to examine whether features of beta events over frontoparietal electrodes were associated with early life stress (ELS) and the related clinical presentation. Eighteen adults with documented ELS (n = 18; ELS + ) and eighteen adults without documented ELS (n = 18; ELS-) completed eyes-closed resting state EEG as part of their participation in a larger childhood stress study. The rate, power, duration, and frequency span of transient oscillatory events were calculated within the beta band at five frontoparietal electrodes. ELS variables were positively associated with beta event rate at Fp2 and beta event duration at Pz, in that greater ELS was associated with higher resting rates and longer durations. These beta event characteristics were used to successfully distinguish between ELS + and ELS- groups. In an independent clinical dataset (n = 25), beta event power at Pz was positively correlated with ELS. Beta events deserve ongoing investigation as a potential disease marker of ELS and subsequent psychiatric treatment outcomes.

Indexed as

Beta RhythmElectroencephalographyStress, PsychologicalAdultFemaleFrontal LobeHumansMaleMiddle AgedParietal LobeYoung AdultBeta bandBiomarkersChildhood adversityEarly life stressOscillatory events

Identifiers

PMID38670050
PMCPMC11193540
OpenAlexW4395480732

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.