Trial reportScientific reports2024
Effects of once- versus twice-weekly eccentric resistance training on muscular function and structure in older adults: a randomised controlled trial.
Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Immediate effects of stretching and eccentric exercise on flexibility, stiffness, and strength in older adults with hamstring tightness and possible sarcopenia: a randomized controlled trial.European journal of applied physiology · 2026Trial
- The effects of simultaneous isometric and eccentric- or concentric-biased exercise on cardiovascular and muscular health of young individuals.European journal of applied physiology · 2026Trial
- High- versus low-volume static stretching and eccentric exercise: a randomized controlled trial in older adults with hamstring tightness and possible sarcopenia.European journal of applied physiology · 2026Article
- Beyond the first bout: Adaptations to repeated injuries across physiological and pathological conditions.Physiological reports · 2026Review
- Muscle quality index and phase angle responses to matched-volume resistance training at different frequencies in older women.Physical activity and nutrition · 2026Article
- High-Velocity, Accentuated Eccentric, or Maximal Elastic Band Resistance Training? Effects of Resistance Training Modalities on Bone Health, Isokinetic Strength, and Systemic Biomarkers in Sedentary Older Adults: A Comparative Study.Healthcare (Basel, Switzerland) · 2025Article
- Submaximal Eccentric Training During Immobilization Does Not Prevent Serial Sarcomere Loss or Impairments in Mechanical Function in Old or Young Rats.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Effect of Eccentric Training with Different Durations, Intensities, and Contraction Velocities on Upper Limb Muscle Strength: A Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Sculpting Success: The Importance of Diet and Physical Activity to Support Skeletal Muscle Health during Weight Loss with New Generation Anti-Obesity Medications.Current developments in nutrition · 2024Review
- Submaximal eccentric resistance training increases serial sarcomere number and improves dynamic muscle performance in old rats.Physiological reports · 2024Article
- Effects of detraining on neuromuscular function and structural adaptations following once- or twice-weekly eccentric resistance training in older adults.Aging clinical and experimental research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Adherence rates to current twice-weekly strength training guidelines are poor among older adults. Eccentric-only training elicits substantial improvements in muscle function/size so the aim of this study was to compare the effects of once- versus twice-weekly eccentric training programmes on muscle function/size in older adults. Thirty-six participants (69.4 ± 6.0 yr) were randomised into non-active control, once-, or twice-weekly training groups. Lower-limb muscle power, strength, and size were assessed at baseline, mid-, and post-eccentric training. Training was performed for 12 min per session at 50% of maximum eccentric strength. Significant increases in power (13%), isometric (17-36%) and eccentric (40-50%) strength, and VL muscle thickness (9-18%) occurred in both training groups following 12 weeks. Minimal muscle soreness was induced throughout the 12 weeks and perceived exertion was consistently lower in the twice-weekly training group. One weekly submaximal eccentric resistance training session over 12 weeks elicits similar improvements in neuromuscular function compared to the currently recommended twice-weekly training dose. Given the substantial improvements in neuromuscular function and previously reported low adherence to current twice-weekly training guidelines, eccentric training may be pivotal to developing a minimal-dose strategy to counteract neuromuscular decline. The trial was registered retrospectively on 24/01/2024 with ISRCTN (trial registration number: ISRCTN68730580).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.