Evidence map›Paper›PMID 38672003›Full record

ArticleBrain sciences2024

A Subtype Perspective on Cognitive Trajectories in Healthy Aging.

Emma A Rodrigues, Gregory J Christie, Theodore Cosco, Faranak Farzan, Andrew Sixsmith, Sylvain Moreno

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Profiles of Aging Based on Cognition, Affect, and Brain Reserve.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Interpretable machine learning for precision cognitive aging.Frontiers in computational neuroscience · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emma A RodriguesSchool of Interactive Arts and Technology, Simon Fraser University, Surrey, BC V3T 0A3, Canada.
Gregory J ChristieCircle Innovation, Simon Fraser University, Surrey, BC V3T 0A3, Canada.
Theodore CoscoDepartment of Gerontology, Simon Fraser University, Vancouver, BC V6B 5K3, Canada.ORCID 0000-0002-9977-8888
Faranak FarzanSchool of Mechatronics and Systems Engineering, Simon Fraser University, Surrey, BC V3T 0A3, Canada.
Andrew SixsmithDepartment of Gerontology, Simon Fraser University, Vancouver, BC V6B 5K3, Canada.
Sylvain MorenoSchool of Interactive Arts and Technology, Simon Fraser University, Surrey, BC V3T 0A3, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive aging is a complex and dynamic process characterized by changes due to genetics and environmental factors, including lifestyle choices and environmental exposure, which contribute to the heterogeneity observed in cognitive outcomes. This heterogeneity is particularly pronounced among older adults, with some individuals maintaining stable cognitive function while others experience complex, non-linear changes, making it difficult to identify meaningful decline accurately. Current research methods range from population-level modeling to individual-specific assessments. In this work, we review these methodologies and propose that population subtyping should be considered as a viable alternative. This approach relies on early individual-specific detection methods that can lead to an improved understanding of changes in individual cognitive trajectories. The improved understanding of cognitive trajectories through population subtyping can lead to the identification of meaningful changes and the determination of timely, effective interventions. This approach can aid in informing policy decisions and in developing targeted interventions that promote cognitive health, ultimately contributing to a more personalized understanding of the aging process within society and reducing the burden on healthcare systems.

Indexed as

cognitive healthhealthy agingheterogeneitysubtypingtrajectories

Identifiers

PMID38672003
PMCPMC11048421

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.