Evidence map›Paper›PMID 38672588›Full record

ArticleCancers2024

Development and Validation of a Deep Learning Model for Histopathological Slide Analysis in Lung Cancer Diagnosis.

Alhassan Ali Ahmed, Muhammad Fawi, Agnieszka Brychcy, Mohamed Abouzid, Martin Witt, Elżbieta Kaczmarek

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alhassan Ali AhmedDepartment of Bioinformatics and Computational Biology, Poznan University of Medical Sciences, 61-806 Poznan, Poland.ORCID 0000-0003-1912-0195
Muhammad FawiSpider Silk Security DMCC, Dubai 282945, United Arab Emirates.ORCID 0009-0007-7210-0528
Agnieszka BrychcyDepartment of Clinical Patomorphology, Heliodor Swiecicki Clinical Hospital of the Poznan University of Medical Sciences, 61-806 Poznan, Poland.ORCID 0000-0003-0606-7778
Mohamed AbouzidDoctoral School, Poznan University of Medical Sciences, 61-806 Poznan, Poland.ORCID 0000-0002-8917-671X
Martin WittDepartment of Anatomy, Poznan University of Medical Sciences, 60-806 Poznan, Poland.ORCID 0000-0002-4538-877X
Elżbieta KaczmarekDepartment of Bioinformatics and Computational Biology, Poznan University of Medical Sciences, 61-806 Poznan, Poland.

Funding

Poznan University of Medical Sciences SDUM-MGB 10/04/23_NMN0000082
6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer-related deaths worldwide. Two of the crucial factors contributing to these fatalities are delayed diagnosis and suboptimal prognosis. The rapid advancement of deep learning (DL) approaches provides a significant opportunity for medical imaging techniques to play a pivotal role in the early detection of lung tumors and subsequent monitoring during treatment. This study presents a DL-based model for efficient lung cancer detection using whole-slide images. Our methodology combines convolutional neural networks (CNNs) and separable CNNs with residual blocks, thereby improving classification performance. Our model improves accuracy (96% to 98%) and robustness in distinguishing between cancerous and non-cancerous lung cell images in less than 10 s. Moreover, the model's overall performance surpassed that of active pathologists, with an accuracy of 100% vs. 79%. There was a significant linear correlation between pathologists' accuracy and years of experience (r Pearson = 0.71, 95% CI 0.14 to 0.93,

Indexed as

convolutional neural networksdeep learninghistopathologylung cancermachine learningmedical diagnosis

Identifiers

PMID38672588
PMCPMC11048051

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.