Evidence map›Paper›PMID 38673000›Full record

ArticleJournal of personalized medicine2024

Exploring Blood Cell Count-Derived Ratios as Practical Diagnostic Tools for Scabies in Vulnerable Populations.

Hoang Thao Giang Nguyen, Ha Long Hai Le, Hoang Viet Nguyen, Huyen My Le, Huy Luong Vu, Pleiades T Inaoka, Ota Tetsuo, Quoc Trung Ly, J Luis Espinoza

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. MAIT Cells in the Bone Marrow of Patients with Aplastic Anemia.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Hoang Thao Giang NguyenFaculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, Japan.ORCID 0009-0002-2188-1073
Ha Long Hai LeDepartment of Biochemistry, Hematology and Immunology, National Hospital of Dermatology and Venereology, Hanoi 100000, Vietnam.ORCID 0009-0001-1668-2902
Hoang Viet NguyenFaculty of Medical Technology, Hanoi Medical University, Hanoi 116001, Vietnam.ORCID 0009-0002-5216-2282
Huyen My LeDepartment of Biochemistry, Hematology and Immunology, National Hospital of Dermatology and Venereology, Hanoi 100000, Vietnam.
Huy Luong VuDepartment of Laser and Skin Care, National Hospital of Dermatology and Venereology, Hanoi 116001, Vietnam.
Pleiades T InaokaFaculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, Japan.ORCID 0000-0002-7973-0705
Ota TetsuoFaculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, Japan.
Quoc Trung LySoctrang Hospital for Women and Children, Soc Trang 950000, Vietnam.
J Luis EspinozaFaculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, Japan.ORCID 0000-0002-1794-6666
Kanazawa University · JPHanoi Medical University · VNVietnam National Children's Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scabies is a neglected tropical disease and represents a considerable global burden. Although consensus diagnostic criteria for scabies have been recently published, diagnosing scabies infestation remains challenging in clinical practice. We investigated the diagnostic utility of complete blood cell count (CBC) and CBC-derived ratios obtained at diagnosis in a set of 167 patients who are Vietnamese with confirmed scabies. These parameters were compared with those of patients with dermatophytosis (N = 800) and urticaria (N = 2023), two diseases frequent in Vietnam, which can present with similar skin manifestations to scabies and tend to pose a diagnostic challenge in vulnerable populations. Our analysis revealed that white blood cell, monocyte, and eosinophil counts were significantly higher among patients with scabies than the other two diseases. Similarly, the monocyte-to-lymphocyte ratio (MLR) and eosinophil-to-lymphocyte ratio (ELR) were significantly higher among patients with scabies. The optimal cut-off values to distinguish scabies from dermatophytosis and urticaria were 0.094 for ELR (sensitivity: 74.85%, specificity: 70.7%) and 0.295 for MLR (sensitivity: 52.69%, specificity: 73.54%). CBC, ELR, and MLR are low-cost and easily calculated parameters that may be helpful for the diagnosis of scabies.

Indexed as

blood cell countdifferential diagnosiseosinophiliainflammation markerscabies

Identifiers

PMID38673000
PMCPMC11050978
OpenAlexW4393352570

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.