Evidence map›Paper›PMID 38673815›Full record

ReviewInternational journal of molecular sciences2024

Atherosclerosis and the Bidirectional Relationship between Cancer and Cardiovascular Disease: From Bench to Bedside-Part 1.

Giuseppina Gallucci, Fabio Maria Turazza, Alessandro Inno, Maria Laura Canale, Nicola Silvestris, Roberto Farì, Alessandro Navazio, Carmine Pinto, Luigi Tarantini

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  4. Inflammaging and Cardiovascular Risk in Old Women.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Giuseppina GallucciIndependent Researcher, 85025 Melfi, Italy.
Fabio Maria TurazzaStruttura Complessa di Cardiologia, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milano, Italy.
Alessandro InnoOncologia Medica, IRCCS Ospedale Sacro Cuore Don Calabria, 37024 Negrar di Valpolicella, Italy.ORCID 0000-0001-6331-6908
Maria Laura CanaleDivision of Cardiology, Azienda USL Toscana Nord-Ovest, Versilia Hospital, 55041 Lido di Camaiore, Italy.
Nicola SilvestrisMedical Oncology Unit, Department of Human Pathology "G.Barresi", University of Messina, 98100 Messina, Italy.
Roberto FarìClinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, 41100 Modena, Italy.ORCID 0009-0003-0405-1390
Alessandro NavazioCardiologia Ospedaliera, Department of Specialized Medicine, AUSL-IRCCS in Tecnologie Avanzate e Modelli Assistenziali in Oncologia, 42100 Reggio Emilia, Italy.ORCID 0000-0001-8417-7783
Carmine PintoProvincial Medical Oncology, Department of Oncology and Advanced Technologies, AUSL-IRCCS in Tecnologie Avanzate e Modelli Assistenziali in Oncologia, 42100 Reggio Emilia, Italy.ORCID 0000-0002-3159-5268
Luigi TarantiniCardiologia Ospedaliera, Department of Specialized Medicine, AUSL-IRCCS in Tecnologie Avanzate e Modelli Assistenziali in Oncologia, 42100 Reggio Emilia, Italy.ORCID 0000-0003-2580-0963
Tecnologie Avanzate (Italy) · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITOspedale Sacro Cuore Don Calabria · ITOspedale Versilia · ITUniversity of Messina · ITUniversity of Modena and Reggio Emilia · IT

Funding

Ministero della Salute Ricerca corrente Annual Program 2025
6 · The paper itself

Abstract

Atherosclerosis, a complex metabolic-immune disease characterized by chronic inflammation driven by the buildup of lipid-rich plaques within arterial walls, has emerged as a pivotal factor in the intricate interplay between cancer and cardiovascular disease. This bidirectional relationship, marked by shared risk factors and pathophysiological mechanisms, underscores the need for a comprehensive understanding of how these two formidable health challenges intersect and influence each other. Cancer and its treatments can contribute to the progression of atherosclerosis, while atherosclerosis, with its inflammatory microenvironment, can exert profound effects on cancer development and outcomes. Both cancer and cardiovascular disease involve intricate interactions between general and personal exposomes. In this review, we aim to summarize the state of the art of translational data and try to show how oncologic studies on cardiotoxicity can broaden our knowledge of crucial pathways in cardiovascular biology and exert a positive impact on precision cardiology and cardio-oncology.

Indexed as

AtherosclerosisCardiovascular DiseasesNeoplasmsAnimalsHumansRisk FactorsTranslational Research, Biomedicalatherosclerosiscancercardiovascular disease (CVD)endotheliumexposomeimmune systeminflammation

Identifiers

PMID38673815
PMCPMC11049833
OpenAlexW4394735153

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.