Evidence map›Paper›PMID 38674042›Full record

ArticleInternational journal of molecular sciences2024

Integrating Proteomics and Transcriptomics Reveals the Potential Pathways of Hippocampal Neuron Apoptosis in Dravet Syndrome Model Mice.

Xuerui Kong, Gaohe Dai, Zhong Zeng, Yi Zhang, Jiarong Gu, Teng Ma, Nina Wang, Jinhai Gu, Yin Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Dravet syndrome: novel insights intoFrontiers in neuroscience · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xuerui KongSchool of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China.
Gaohe DaiKey Laboratory of Craniocerebral Diseases, Ningxia Medical University, Yinchuan 750004, China.
Zhong ZengSchool of Clinical Medicine, Ningxia Medical University, Yinchuan 750004, China.
Yi ZhangKey Laboratory of Craniocerebral Diseases, Ningxia Medical University, Yinchuan 750004, China.
Jiarong GuSchool of Public Health, Ningxia Medical University, Yinchuan 750004, China.
Teng MaSchool of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China.
Nina WangSchool of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China.
Jinhai GuKey Laboratory of Craniocerebral Diseases, Ningxia Medical University, Yinchuan 750004, China.
Yin WangSchool of Basic Medicine, Ningxia Medical University, Yinchuan 750004, China.
Ningxia Medical University · CN

Funding

the National Natural Science Foundation of China 82260269the Natural Science Foundation of Ningxia 2020AAC03152the Natural Science Foundation of Ningxia 2021AAC03121
6 · The paper itself

Abstract

An important component contributing to the onset of epilepsy is the death of hippocampal neurons. Several studies have shown that Dravet syndrome model mice:

Indexed as

ApoptosisDisease Models, AnimalEpilepsies, MyoclonicHippocampusMice, KnockoutNAV1.1 Voltage-Gated Sodium ChannelNeuronsProteomicsTranscriptomeAnimalsGene Expression ProfilingHypoxia-Inducible Factor 1, alpha SubunitMiceSignal TransductionHypoxia-Inducible Factor 1, alpha SubunitNAV1.1 Voltage-Gated Sodium ChannelScn1a protein, mouseDravet syndromeHIF-1αneuron apoptosisp21proteomicsScn1a micetranscriptomicsVHL

Identifiers

PMID38674042
PMCPMC11050081
OpenAlexW4394932799

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.