Evidence map›Paper›PMID 38674209›Full record

ReviewMedicina (Kaunas, Lithuania)2024

The Many Faces of Metabolic Dysfunction-Associated Fatty Liver Disease Treatment: From the Mediterranean Diet to Fecal Microbiota Transplantation.

Ludovico Abenavoli, Maria Luisa Gambardella, Giuseppe Guido Maria Scarlata, Ilaria Lenci, Leonardo Baiocchi, Francesco Luzza

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Defining reference values for the gut microbiota in a Southern European population.Frontiers in cellular and infection microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ludovico AbenavoliDepartment of Health Sciences, University "Magna Graecia", Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0002-5922-1524
Maria Luisa GambardellaDepartment of Health Sciences, University "Magna Graecia", Viale Europa, 88100 Catanzaro, Italy.
Giuseppe Guido Maria ScarlataDepartment of Health Sciences, University "Magna Graecia", Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0002-7084-8264
Ilaria LenciHepatology and Liver Transplant Unit, University of Tor Vergata, Via Montpellier, 00133 Rome, Italy.ORCID 0000-0001-5704-9890
Leonardo BaiocchiHepatology and Liver Transplant Unit, University of Tor Vergata, Via Montpellier, 00133 Rome, Italy.
Francesco LuzzaDepartment of Health Sciences, University "Magna Graecia", Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0001-5120-1046
Magna Graecia University · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gastrointestinal tract is inhabited by the gut microbiota. The main phyla are Firmicutes and Bacteroidetes. In non-alcoholic fatty liver disease, now renamed metabolic dysfunction-associated fatty liver disease (MAFLD), an alteration in Firmicutes and Bacteroidetes abundance promotes its pathogenesis and evolution into non-alcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. For this reason, early treatment is necessary to counteract its progression. The aim of the present narrative review is to evaluate the different therapeutic approaches to MAFLD. The most important treatment for MAFLD is lifestyle changes. In this regard, the Mediterranean diet could be considered the gold standard in the prevention and treatment of MAFLD. In contrast, a Western diet should be discouraged. Probiotics and fecal microbiota transplantation seem to be valid, safe, and effective alternatives for MAFLD treatment. However, more studies with a longer follow-up and with a larger cohort of patients are needed to underline the more effective approaches to contrasting MAFLD.

Indexed as

Diet, MediterraneanFecal Microbiota TransplantationNon-alcoholic Fatty Liver DiseaseGastrointestinal MicrobiomeHumansProbioticsgut–liver axisleaky gutMediterranean dietprobioticssteatosis

Identifiers

PMID38674209
PMCPMC11051743
OpenAlexW4393357678

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.