Evidence map›Paper›PMID 38674407›Full record

ArticleGenes2024

Factors Influencing Mortality in Children with Central Nervous System Tumors: A Cohort Study on Clinical Characteristics and Genetic Markers.

Luz María Torres-Espíndola, Juan Carlos Pérez-De Marcos, Manuel Castillejos-López, Liliana Velasco-Hidalgo, Rocío Cárdenas-Cardós, Armando De Uña-Flores, Citlaltepetl Salinas-Lara, Silvia Caballero-Salazar, Rosario Fernández-Plata, Arnoldo Aquíno-Gálvez

Open access · goldAbstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Luz María Torres-EspíndolaPharmacology Laboratory, National Institute of Pediatrics, Mexico City 04530, Mexico.
Juan Carlos Pérez-De MarcosPharmacology Laboratory, National Institute of Pediatrics, Mexico City 04530, Mexico.
Manuel Castillejos-LópezHospital Epidemiology and Infectology Unit, National Institute of Respiratory Diseases Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0001-8689-9755
Liliana Velasco-HidalgoOncology Service, National Institute of Pediatrics, Mexico City 04530, Mexico.
Rocío Cárdenas-CardósOncology Service, National Institute of Pediatrics, Mexico City 04530, Mexico.
Armando De Uña-FloresRadiology and Imaging Service, National Institute of Pediatrics, Mexico City 04530, Mexico.
Citlaltepetl Salinas-LaraDepartment of Neuropathology, National Institute of Neurology and Neurosurgery, Manuel Velasco Suárez, Mexico City 14269, Mexico.
Silvia Caballero-SalazarExperimental Oncology Laboratory, National Institute of Pediatrics, Mexico City 04530, Mexico.ORCID 0000-0003-4386-7395
Rosario Fernández-PlataHospital Epidemiology and Infectology Unit, National Institute of Respiratory Diseases Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-2971-0845
Arnoldo Aquíno-GálvezMolecular Biology Laboratory, Pulmonary Fibrosis Department, National Institute of Respiratory Diseases Ismael Cosío Villegas, Mexico City 14080, Mexico.ORCID 0000-0002-2869-5516
Instituto Nacional de Neurología y Neurocirugía · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug resistance (MDR) commonly leads to cancer treatment failure because cancer cells often expel chemotherapeutic drugs using ATP-binding cassette (ABC) transporters, which reduce drug levels within the cells. This study investigated the clinical characteristics and single nucleotide variant (SNV) in

Indexed as

Central Nervous System NeoplasmsMultidrug Resistance-Associated Protein 2Polymorphism, Single NucleotideAdolescentATP-Binding Cassette, Sub-Family C ProteinsATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily G, Member 2Biomarkers, TumorChildChild, PreschoolCohort StudiesFemaleGenetic MarkersHumansInfantMaleABCB1 protein, humanABCC2 protein, humanATP-Binding Cassette, Sub-Family C ProteinsATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily G, Member 2Biomarkers, TumorGenetic MarkersMultidrug Resistance-Associated Protein 2Neoplasm ProteinsABC genecentral nervous system tumorsmortalitypediatric patientsSNV

Identifiers

PMID38674407
PMCPMC11050576
OpenAlexW4394604567

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.