Evidence map›Paper›PMID 38674815›Full record

ReviewNutrients2024

The Interplay between Endocrine-Disrupting Chemicals and the Epigenome towards Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comprehensive Review.

Evangelia Mentsiou Nikolaou, Ioanna Panagiota Kalafati, George V Dedoussis

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Environmental Endocrine-Disrupting Chemicals and Metabolic Dysfunction-Associated Steatotic Liver Disease.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Review
  3. Review
  4. Protective Effects ofFood science & nutrition · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Evangelia Mentsiou NikolaouDepartment of Nutrition and Dietetics, School of Health and Education, Harokopio University of Athens, 17676 Athens, Greece.ORCID 0009-0007-7965-155X
Ioanna Panagiota KalafatiDepartment of Nutrition and Dietetics, School of Health and Education, Harokopio University of Athens, 17676 Athens, Greece.ORCID 0000-0001-5572-7491
George V DedoussisDepartment of Nutrition and Dietetics, School of Health and Education, Harokopio University of Athens, 17676 Athens, Greece.ORCID 0000-0002-7798-6221
Harokopio University of Athens · GRUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD), described as the most prominent cause of chronic liver disease worldwide, has emerged as a significant public health issue, posing a considerable challenge for most countries. Endocrine-disrupting chemicals (EDCs), commonly found in daily use items and foods, are able to interfere with nuclear receptors (NRs) and disturb hormonal signaling and mitochondrial function, leading, among other metabolic disorders, to MASLD. EDCs have also been proposed to cause transgenerationally inherited alterations leading to increased disease susceptibility. In this review, we are focusing on the most prominent linking pathways between EDCs and MASLD, their role in the induction of epigenetic transgenerational inheritance of the disease as well as up-to-date practices aimed at reducing their impact.

Indexed as

Endocrine DisruptorsAnimalsEpigenesis, GeneticEpigenomeFatty LiverHumansMetabolic DiseasesNon-alcoholic Fatty Liver DiseaseReceptors, Cytoplasmic and NuclearEndocrine DisruptorsReceptors, Cytoplasmic and NucleardietDNA methylationendocrine-disrupting chemicals (EDCs)epigenetic changesgene–environment interactionshistone alterationsmetabolic dysfunction-associated steatotic liver disease (MASLD)microRNAstransgenerational inheritance

Identifiers

PMID38674815
PMCPMC11054068
OpenAlexW4394726445

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.