Evidence map›Paper›PMID 38675400›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

The Genetic Landscape of Systemic Rheumatic Diseases: A Comprehensive Multigene-Panel Study Identifying Key Gene Polymorphisms.

Elena Rita Simula, Seyedesomaye Jasemi, Davide Cossu, Pietro Carmelo Manca, Daria Sanna, Fabio Scarpa, Gianfranco Meloni, Roberto Cusano, Leonardo Antonio Sechi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Elena Rita SimulaDipartimento di Scienze Biomediche, Università di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-8946-2679
Seyedesomaye JasemiDipartimento di Scienze Biomediche, Università di Sassari, 07100 Sassari, Italy.
Davide CossuDipartimento di Scienze Biomediche, Università di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0557-9467
Pietro Carmelo MancaS.C. Servizio Immunotrasfusionale, Azienda Ospedaliero-Universitaria di Sassari, 07100 Sassari, Italy.
Daria SannaDipartimento di Scienze Biomediche, Università di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3058-4663
Fabio ScarpaDipartimento di Scienze Biomediche, Università di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3501-714X
Gianfranco MeloniDipartimento di Medicina, Chirurgia e Farmacia, Università di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0604-8924
Roberto CusanoCentro di Ricerca, Sviluppo, Studi Superiori in Sardegna (CRS4), Pula, 09100 Cagliari, Italy.
Leonardo Antonio SechiDipartimento di Scienze Biomediche, Università di Sassari, 07100 Sassari, Italy.ORCID 0000-0003-0566-2049
University of Sassari · ITAzienda Ospedaliero Universitaria di Sassari · ITCenter for Advanced Studies Research and Development in Sardinia · IT

Funding

Fondazione di Sardegna 2017 Fondazione di Sardegna to LAS 2017MUR PRIN 2022 n: 2022BP837R to LASRegione autonoma della Sardegna legge regionale 12, 22 Dicembre 2022 n. 22 to LASUNISS Fondi Ateneo per la ricerca to LAS.
6 · The paper itself

Abstract

Systemic rheumatic diseases, including conditions such as rheumatoid arthritis, Sjögren's syndrome, systemic sclerosis, and systemic lupus erythematosus, represent a complex array of autoimmune disorders characterized by chronic inflammation and diverse clinical manifestations. This study focuses on unraveling the genetic underpinnings of these diseases by examining polymorphisms in key genes related to their pathology. Utilizing a comprehensive genetic analysis, we have documented the involvement of these genetic variations in the pathogenesis of rheumatic diseases. Our study has identified several key polymorphisms with notable implications in rheumatic diseases. Polymorphism at chr11_112020916 within the

Indexed as

autoimmunitypolymorphismsystemic rheumatic diseases

Identifiers

PMID38675400
PMCPMC11054024
OpenAlexW4393254286

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.