Evidence mapPaperPMID 38675423Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Potential Anti-Inflammatory and Anti-Fatigue Effects of an Oral Food Supplement in Long COVID Patients.

Annalisa Noce, Giulia Marrone, Manuela Di Lauro, Chiara Vita, Giulia Montalto, Gloria Giorgino, Carlo Chiaramonte, Cartesio D'Agostini, Sergio Bernardini, Massimo Pieri

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Impact of nutrition on long COVID.Sports medicine and health science · 2026
    Review
  3. Article
  4. Therapeutic Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Annalisa NoceUOSD Nephrology and Dialysis, Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-1310-3730
Giulia MarroneUOSD Nephrology and Dialysis, Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-5854-2086
Manuela Di LauroUOSD Nephrology and Dialysis, Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-8118-1330
Chiara VitaQuMAP-PIN, University Center "Città di Prato" Educational and Scientific Services for the University of Florence, 59100 Prato, Italy.ORCID 0000-0001-9190-6550
Giulia MontaltoSchool of Specialization in Nephrology, University of Rome Tor Vergata, 00133 Rome, Italy.
Gloria GiorginoSchool of Specialization in Nephrology, University of Rome Tor Vergata, 00133 Rome, Italy.
Carlo ChiaramonteDepartment of Statistics, University of Rome Tor Vergata, 00133 Rome, Italy.
Cartesio D'AgostiniDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Sergio BernardiniDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Massimo PieriDepartment of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-3463-0268
University of Rome Tor Vergata · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long coronavirus disease (COVID) syndrome leads to chronic inflammatory state onset that can have a multisystem impact and compromise organ function. Moreover, long COVID syndrome is often characterized by the presence of chronic fatigue, which affects subjects' daily activities and worsens their quality of life. The aim of our double-blind, placebo-controlled randomized trial (protocol code RS 150.21, approved on 4 November 2021) was to evaluate the beneficial effects of the consumption of 2 cps/day, for two months, of an oral food supplement (OFS), based on

Indexed as

adjuvant treatmentcytokine stormfatigueinflammatory statelong COVID syndromenatural bioactive compoundsoxidative stressquality of lifeSARS-CoV-2

Identifiers

PMID38675423
PMCPMC11053797
OpenAlexW4393992837

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.