Evidence mapPaperPMID 38675719Full record

ReviewMolecules (Basel, Switzerland)2024

The Ocean's Pharmacy: Health Discoveries in Marine Algae.

Mélanie Silva, Dorit Avni, João Varela, Luísa Barreira

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mélanie SilvaCentre of Marine Sciences, University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-0460-646X
Dorit AvniMIGAL Galilee Institute, Kiryat Shmona 1106000, Israel.
João VarelaCentre of Marine Sciences, University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0003-3101-693X
Luísa BarreiraCentre of Marine Sciences, University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-4077-855X
University of Algarve · PTMigal - Galilee Technology Center · IL

Funding

doctoral fellowship 2022.12681.BDANAEuropean Union through the ALGAE4IBD project /EC/H2020/101000501/EUFCT-Foundation for Science and Technology LA/P/0101/2020FCT-Foundation for Science and Technology UIDB/04326/2020FCT-Foundation for Science and Technology UIDP/04326/2020
6 · The paper itself

Abstract

Non-communicable diseases (NCDs) represent a global health challenge, constituting a major cause of mortality and disease burden in the 21st century. Addressing the prevention and management of NCDs is crucial for improving global public health, emphasizing the need for comprehensive strategies, early interventions, and innovative therapeutic approaches to mitigate their far-reaching consequences. Marine organisms, mainly algae, produce diverse marine natural products with significant therapeutic potential. Harnessing the largely untapped potential of algae could revolutionize drug development and contribute to combating NCDs, marking a crucial step toward natural and targeted therapeutic approaches. This review examines bioactive extracts, compounds, and commercial products derived from macro- and microalgae, exploring their protective properties against oxidative stress, inflammation, cardiovascular, gastrointestinal, metabolic diseases, and cancer across in vitro, cell-based, in vivo, and clinical studies. Most research focuses on macroalgae, demonstrating antioxidant, anti-inflammatory, cardioprotective, gut health modulation, metabolic health promotion, and anti-cancer effects. Microalgae products also exhibit anti-inflammatory, cardioprotective, and anti-cancer properties. Although studies mainly investigated extracts and fractions, isolated compounds from algae have also been explored. Notably, polysaccharides, phlorotannins, carotenoids, and terpenes emerge as prominent compounds, collectively representing 42.4% of the investigated compounds.

Indexed as

MicroalgaeAnimalsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsAquatic OrganismsBiological ProductsHumansOceans and SeasOxidative StressSeaweedAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsBiological Productsalgaebioactivitycell assayshealthin vitro studiesin vivo studiesmacroalgaemicroalgaenon-communicable diseases

Identifiers

PMID38675719
PMCPMC11055030
OpenAlexW4394999552

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.