Evidence map›Paper›PMID 38675837›Full record

ReviewViruses2024

Advances in Antiretroviral Therapy for Patients with Human Immunodeficiency Virus-Associated Tuberculosis.

Xiaoqin Le, Yinzhong Shen

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xiaoqin LeDepartment of Infection and Immunity, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.ORCID 0000-0002-3295-8702
Yinzhong ShenDepartment of Infection and Immunity, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.ORCID 0000-0002-7604-5139
Shanghai Public Health Clinical Center · CN

Funding

Shanghai Municipal Science and Technology Major Project, Shanghai Science and Technology Committee ZD2021CY001Shanghai Science and Technology Commission Medical Innovation Research Special Major Project 21Y31900400Shanghai Science and Technology Commission Shanghai infectious diseases (AIDS) Clinical Medical Research Center Project 20MC1920100Shanghai Shenkang Hospital Development Center Clinical Science and Technology Innovation Project SHDC22021317Shenkang Hospital Development Center Clinical Research Basic Support Project SHDC2020CR6025
6 · The paper itself

Abstract

Tuberculosis is one of the most common opportunistic infections and a prominent cause of death in patients with human immunodeficiency virus (HIV) infection, in spite of near-universal access to antiretroviral therapy (ART) and tuberculosis preventive therapy. For patients with active tuberculosis but not yet receiving ART, starting ART after anti-tuberculosis treatment can complicate clinical management due to drug toxicities, drug-drug interactions and immune reconstitution inflammatory syndrome (IRIS) events. The timing of ART initiation has a crucial impact on treatment outcomes, especially for patients with tuberculous meningitis. The principles of ART in patients with HIV-associated tuberculosis are specific and relatively complex in comparison to patients with other opportunistic infections or cancers. In this review, we summarize the current progress in the timing of ART initiation, ART regimens, drug-drug interactions between anti-tuberculosis and antiretroviral agents, and IRIS.

Indexed as

Antitubercular AgentsDrug InteractionsHIV InfectionsImmune Reconstitution Inflammatory SyndromeTuberculosisAIDS-Related Opportunistic InfectionsAnti-HIV AgentsAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveHumansTreatment OutcomeAnti-HIV AgentsAnti-Retroviral AgentsAntitubercular Agentsantiretroviral therapyHIV infectionimmune reconstitution inflammatory syndrometuberculosis

Identifiers

PMID38675837
PMCPMC11054420
OpenAlexW4393164089

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.