Evidence map›Paper›PMID 38679583›Full record

ArticleJournal of evidence-based integrative medicine

Effect of Aqueous Extract of Unripe

Collins Azubuike Onyeto, Akachukwu Marytheresa Onwuka, Ikechukwu Emmanuel Peter, Chukwuemeka Sylvester Nworu, Peter Achunike Akah

Abstract read
In one paragraph

Article in Journal of evidence-based integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Collins Azubuike OnyetoDepartment of Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.
Akachukwu Marytheresa OnwukaDepartment of Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.ORCID 0000-0002-8282-5983
Ikechukwu Emmanuel PeterDepartment of Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.
Chukwuemeka Sylvester NworuDepartment of Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.
Peter Achunike AkahDepartment of Pharmacology & Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAqueous extract of unripe

methodsAqueous extracts obtained by maceration were analyzed for acute and subacute toxicity and for the presence of phytochemical constituents using standard procedures. The extract (100, 500, and 1000 mg/kg) was administered daily to rats of both sexes for 28 d. Blood samples collected on days 0 and 28 were assessed for follicle-stimulating hormone (FSH), luteinizing hormone (LH), catalase (CAT), superoxide dismutase (SOD), and malondialdehyde (MDA). Testes and ovaries were harvested for histopathological analysis. Sperm were also collected to determine the sperm count and motility.

resultsPhytochemical screening revealed the presence of saponins, tannins, alkaloids, and resins. After an oral dose of up to 5000 mg/kg, there were no deaths in the acute toxicity test. The extract (500 mg/kg) significantly (

conclusionUnripe

Indexed as

Follicle Stimulating HormoneLuteinizing HormoneMusaPlant ExtractsAnimalsCatalaseFemaleFruitMaleMalondialdehydeNigeriaOvaryRatsRats, WistarReproductionSperm CountCatalaseFollicle Stimulating HormoneLuteinizing HormoneMalondialdehydePlant ExtractsSuperoxide Dismutaseaqueous extractMusa paradisiacaovaryrodentstestestoxicity

Identifiers

PMID38679583
PMCPMC11057342

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.