Evidence map›Paper›PMID 38679671›Full record

ArticleLasers in medical science2024

Enhancing nerve regeneration in infraorbital nerve injury rat model: effects of vitamin B complex and photobiomodulation.

Daniel Oliveira Martins, Daniel Pereira Marques, Marucia Chacur

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Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel Oliveira MartinsDivision of Neuroscience/Hospital Sírio-Libânes, Street Daher Cutait 69, São Paulo, SP, 01308-060, Brazil. danomartins82@gmail.com.ORCID http://orcid.org/0000-0003-3441-1820
Daniel Pereira MarquesDepartmento de Anatomia, Laboratory of Functional Neuroanatomy of Pain, Universidade de São Paulo Instituto de Ciências Biomédicas, São Paulo, SP, Brazil.
Marucia ChacurDepartmento de Anatomia, Laboratory of Functional Neuroanatomy of Pain, Universidade de São Paulo Instituto de Ciências Biomédicas, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-0172-4110

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 157284/2017-4Conselho Nacional de Desenvolvimento Científico e Tecnológico 405853/2018-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/24533-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/24256-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/05218-5
6 · The paper itself

Abstract

Orofacial nerve injuries may result in temporary or long-term loss of sensory function and decreased quality of life in patients. B vitamins are required for DNA synthesis and the repair and maintenance of phospholipids. In particular, vitamins B1, B6, and B12 are essential for neuronal function. Deficiency in vitamin B complex (VBC) has been linked to increased oxidative stress, inflammation and demyelination. Photobiomodulation (PBM) has antioxidant activity and is neuroprotective. In addition, a growing literature attests to the positive effects of PBM on nerve repair. To assess the effect of PBM and VBC on regenerative process we evaluated the expression of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), myelin basic protein (MBP), laminin and neurofilaments (NFs) using Western blotting to identify regenerative pattern after chronic constriction injury of the infraorbital nerve (CCI IoN) treated by PBM, VBC or its combination. After CCI IoN, the rats were divided into six groups naive, sham, injured (CCI IoN), treated with photobiomodulation (904 nm, 6.23 J/cm

Indexed as

Brain-Derived Neurotrophic FactorDisease Models, AnimalLow-Level Light TherapyNerve Growth FactorNerve RegenerationVitamin B ComplexAnimalsFacial Nerve InjuriesLamininMaleMyelin Basic ProteinRatsRats, WistarBrain-Derived Neurotrophic FactorLamininMyelin Basic ProteinNerve Growth FactorVitamin B ComplexNeural regenerationNeurotrophic factorsPeripheral nerve injuriesPhotobiomodulationVitamin B complex

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.