Evidence map›Paper›PMID 38680427›Full record

ArticleInformation processing in medical imaging : proceedings of the ... conference2023

sEBM: Scaling Event Based Models to Predict Disease Progression via Implicit Biomarker Selection and Clustering.

Raghav Tandon, Anna Kirkpatrick, Cassie S Mitchell

Abstract read
In one paragraph

Article in Information processing in medical imaging : proceedings of the ... conference, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Stage-Aware Event-Based Modeling (SA-EBM) for Disease Progression.Proceedings of machine learning research · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raghav TandonLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA 30332, USA.ORCID 0000-0003-2603-4930
Anna KirkpatrickLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA 30332, USA.ORCID 0000-0002-8737-1132
Cassie S MitchellLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA 30332, USA.ORCID 0000-0002-5472-6355

Funding

Regulatory and Human Study Operations (RHSO) Core CU19AG065169 · NIA · UNIVERSITY OF ARIZONA · PI BARNES, CAROL A. · 2021 to 2025
$59.8M
The Emory Healthy Brain Study: Discovering Predictive Biomarkers for Alzheimer's DiseaseR01AG070937 · NIA · EMORY UNIVERSITY · PI LAH, JAMES J · 2021 to 2025
$35.2M
Inflamm-aging of osteoprogenitor cells: A therapeutic target for improved bone healing - Resubmission - 1 - Revision - 3R01AG056169 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEUCHT, PHILIPP · 2018 to 2022
$2.4M
Inflamm-aging of osteoprogenitor cells: A therapeutic target for improved bone healingR56AG056169 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEUCHT, PHILIPP · 2023 to 2023
$347k
NIA NIH HHS R01 AG056169NIA NIH HHS R01 AG070937NIA NIH HHS R56 AG056169NIA NIH HHS U19 AG065169
6 · The paper itself

Abstract

The Event Based Model (EBM) is a probabilistic generative model to explore biomarker changes occurring as a disease progresses. Disease progression is hypothesized to occur through a sequence of biomarker dysregulation "events". The EBM estimates the biomarker dysregulation event sequence. It computes the data likelihood for a given dysregulation sequence, and subsequently evaluates the posterior distribution on the dysregulation sequence. Since the posterior distribution is intractable, Markov Chain Monte-Carlo is employed to generate samples under the posterior distribution. However, the set of possible sequences increases as

Indexed as

bayesian learningbiomarker clusteringdisease progression modelingprognostic biomarker selection

Identifiers

PMID38680427
PMCPMC11056195

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.