Evidence mapPaperPMID 38682425Full record

ArticleThe British journal of surgery2024

Cohort study on incidence of new-onset type 2 diabetes in patients after bariatric surgery and matched controls.

Viiko Vahtera, Jukka Pajarinen, Mika Kivimäki, Jenni Ervasti, Jaana Pentti, Sari Stenholm, Jussi Vahtera, Paulina Salminen

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Article in The British journal of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Viiko VahteraDepartment of Surgery, Päijät-Häme Central Hospital, Lahti, Finland.ORCID 0009-0008-0547-5757
Jukka PajarinenDepartment of Plastic and Reconstructive Surgery, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
Mika KivimäkiFinnish Institute of Occupational Health, Finland.ORCID 0000-0002-4699-5627
Jenni ErvastiFinnish Institute of Occupational Health, Finland.ORCID 0000-0001-9113-2428
Jaana PenttiClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Sari StenholmDepartment of Public Health, University of Turku and Turku University Hospital, Turku, Finland.
Jussi VahteraDepartment of Public Health, University of Turku and Turku University Hospital, Turku, Finland.ORCID 0000-0002-6036-061X
Paulina SalminenDepartment of Surgery, University of Turku, Turku, Finland.ORCID 0000-0001-6435-9264

Funding

NIA NIH HHS R01 AG056477Wellcome TrustWellcome Trust 221854/Z/20/Z
6 · The paper itself

Abstract

backgroundMetabolic bariatric surgery the reduces risk of new-onset type 2 diabetes in individuals with obesity, but it is unclear whether the benefit varies by sex, age, or socioeconomic status. The aim was to assess the risk of new-onset type 2 diabetes after metabolic bariatric surgery in these subgroups.

methodsThe Finnish Public Sector study, a follow-up study with matched controls nested in a large employee cohort, included patients without type 2 diabetes and with a diagnosis of obesity or self-reported BMI of at least 35 kg/m2. For each patient who had laparoscopic metabolic bariatric surgery (2008-2016), two propensity-score matched controls were selected. New-onset type 2 diabetes was ascertained from linked records from national health registries.

resultsThe study included a total of 917 patients and 1811 matched controls with obesity. New-onset type 2 diabetes was diagnosed in 15 of the patients who had metabolic bariatric surgery (4.1 per 1000 person-years) and 164 controls (20.2 per 1000 person-years). The corresponding rate ratio (RR) was 0.20 (95% c.i. 0.12 to 0.35) and the rate difference (RD) was -16.1 (-19.8 to -12.3) per 1000 person-years. The risk reduction was more marked in individuals of low socioeconomic status (RR 0.10 (0.04 to 0.26) and RD -20.6 (-25.6 to -15.5) per 1000 person-years) than in those with higher socioeconomic status (RR 0.35 (0.18 to 0.66) and RD -11.5 (-16.9 to -6.0) per 1000 person-years) (Pinteraction = 0.017). No differences were observed between sexes or age groups.

conclusionMetabolic bariatric surgery was associated with a reduced risk of new-onset type 2 diabetes in men and women and in all age groups. The greatest benefit was observed in individuals of low socioeconomic status.

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 2AdultCase-Control StudiesFemaleFinlandFollow-Up StudiesHumansIncidenceMaleMiddle AgedObesityObesity, MorbidRisk Factors

Identifiers

PMID38682425
PMCPMC11056794

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.