Evidence map›Paper›PMID 38686193›Full record

ArticleFrontiers in oncology2024

Case report: A germline

Jun Qian, Min Peng, Yanan Li, Wei Liu, Xinwei Zou, Huafei Chen, Sujuan Zhou, Sheng Xiao, Jinhua Zhou

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Role of alternative splicing in cancer progression.Irish journal of medical science · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jun Qian *Department of Gynecology and Obstetrics, The First Affiliated Hospital of Soochow University, Suzhou, China.
Min Peng *Department of Gynecology and Obstetrics, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yanan LiMolecular Genetics Laboratory, Suzhou Sano Precision Medicine Ltd., Suzhou, China.
Wei LiuDepartment of Gynecology and Obstetrics, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xinwei ZouDepartment of Gynecology and Obstetrics, The First Affiliated Hospital of Soochow University, Suzhou, China.
Huafei ChenMolecular Genetics Laboratory, Suzhou Sano Precision Medicine Ltd., Suzhou, China.
Sujuan ZhouMolecular Genetics Laboratory, Suzhou Sano Precision Medicine Ltd., Suzhou, China.
Sheng XiaoDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Jinhua ZhouDepartment of Gynecology and Obstetrics, The First Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Genome instability plays a crucial role in promoting tumor development. Germline mutations in genes responsible for DNA repair are often associated with familial cancer syndromes. A noticeable exception is the Case presentation: In this report, we present a patient diagnosed with ovarian clear cell carcinoma who has a family history of cancer. Her relatives include a grandfather with esophageal cancer, a father with gastric cancer, and an uncle with a brain tumor. The patient carried a typical genomic profile of clear cell carcinoma including mutations in Conclusion: This case highlights a rare germline

Indexed as

CHEK1germline mutationinherited cancerovarian cancersplicing error

Identifiers

PMID38686193
PMCPMC11056527

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.