Evidence map›Paper›PMID 38687055›Full record

ArticlemSphere2024

The interplay between electron transport chain function and iron regulatory factors influences melanin formation in

Peng Xue, Eddy Sánchez-León, Guanggan Hu, Christopher W J Lee, Braydon Black, Anna Brisland, Haohua Li, Won Hee Jung, James W Kronstad

Abstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Assessing the Anti-Cryptococcus Antifungal Potential of Artemisinin.International journal of molecular sciences · 2025
    Article
  9. Transcription Factors Fzc9 and Pdr802 Regulate ATP Levels and Metabolism inInternational journal of molecular sciences · 2025
    Article
  10. Review
  11. Polystyrene nanoparticles reduce theFrontiers in cellular and infection microbiology · 2025
    Article
  12. Puf4 -mediated oxidative stress virulence attenuation inFrontiers in cellular and infection microbiology · 2025
    Article
  13. Article
  14. Evidence for the role of Irk2 and Irk5 in ATP and metabolism regulation inFrontiers in cellular and infection microbiology · 2025
    Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Peng Xue *Michael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Eddy Sánchez-León *Michael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Guanggan HuMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Christopher W J LeeMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Braydon BlackMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Anna BrislandMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Haohua LiMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Won Hee JungDepartment of Systems Biotechnology, Chung-Ang University, Anseong, South Korea.ORCID 0000-0002-6920-0233
James W KronstadMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-4240-6976

Funding

Comparative and functional genomics of C. neoformansR01AI053721 · NIAID · UNIVERSITY OF BRITISH COLUMBIA · PI KRONSTAD, JAMES W · 2003 to 2024
$5.4M
NIAID NIH HHS R01 AI053721
6 · The paper itself

Abstract

Mitochondrial functions are critical for the ability of the fungal pathogen

Indexed as

Cryptococcus neoformansMelaninsElectron TransportElectron Transport Chain Complex ProteinsFungal ProteinsGene Expression Regulation, FungalIronIron-Regulatory ProteinsMitochondriaOxidative StressTranscription FactorsVirulence FactorsElectron Transport Chain Complex ProteinsFungal ProteinsIronIron-Regulatory ProteinsMelaninsTranscription FactorsVirulence Factorselectron transport chainfungal pathogenesisiron regulationmelanin formationreactive oxygen speciesRNA-Seq

Identifiers

PMID38687055
PMCPMC11237718

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.