ArticleProceedings of the National Academy of Sciences of the United States of America2024
CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV.
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9citing papers in PubMed
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Who cites it
9 citing papers in PubMed.
- Investigating the Effects of a CCR3 Antagonist and SP-A Eosinophil Suppressor Tetrapeptide-Transduced Mesenchymal Stem Cells in Allergic Asthma.Applied biochemistry and biotechnology · 2026Article
- Ginsenoside Rg1 Ameliorates the Learning and Memory Deficits of 5xFAD Mice by Inhibiting CCR3 Activity: Insights from In Vivo and In Vitro Investigations.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Type 2 immune history imprints local training in nerve and airway associated interstitial macrophages (NAMs) for disease tolerance during lethal respiratory viral infection.Research square · 2026Article
- Machine Learning-Based Sialylation-Associated Gene Signature Predicts Prognosis and Immune Landscape in Hepatocellular Carcinoma: Validation via Multi-Omics Analysis and in vitro Assays.Journal of hepatocellular carcinoma · 2026Article
- Multi-omics analysis of ST3GAL4-mediated lacto/neolacto glycosphingolipid metabolism reveals immune evasion and poor prognosis in TNBC.Frontiers in immunology · 2026Article
- Article
- Transcriptional Profiling of Abomasal Mucosa from Young Calves Experimentally Infected withInternational journal of molecular sciences · 2025Article
- Eosinophils in Rheumatoid Arthritis: A Multifaceted Role in the Pathogenesis of the Disease.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2025Article
- Regulation of eosinophil recruitment and heterogeneity during allergic airway inflammation.Frontiers in allergy · 2025Review
Corrections and comments
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Authors and funding
20 authors.
Roland ImmlerInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.ORCID 0000-0002-4086-7528
Katrin NussbaumerInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.
Axel DoernerDepartment of Neonatology, University of Heidelberg, Heidelberg 69120, Germany.
Omar El BounkariDivision of Vascular Biology, Institute for Stroke and Dementia Research, Ludwig-Maximilians-Universität, München 81377, Germany.ORCID 0000-0002-3051-2096
Silke HuberInstitute of Immunology, Ludwig-Maximilians-Universität München, München 80336, Germany.
Janine AbischInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.
Matteo NapoliInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.
Sarah SchmidtInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.
Andreas MargrafInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.ORCID 0000-0002-6539-6478
Monika PruensterInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.ORCID 0000-0001-8573-6866
Ina RohwedderInstitute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.
Baerbel Lange-Sperandiovon Haunersches Kinderspital, Klinikum der Universität München, Ludwig-Maximilians-Universität, München 80336, Germany.
Marcus A MallDepartment of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Berlin, Berlin 13353, Germany.ORCID 0000-0002-4057-2199
Renske de JongCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, München 80802, Germany.
Caspar OhnmachtCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, München 80802, Germany.
Juergen BernhagenDivision of Vascular Biology, Institute for Stroke and Dementia Research, Ludwig-Maximilians-Universität, München 81377, Germany.ORCID 0000-0003-2996-2652
David VoehringerInstitute of Immunology, Ludwig-Maximilians-Universität München, München 80336, Germany.ORCID 0000-0001-6650-0639
Jamey D MarthSanford Burnham Prebys Medical Discovery Institute, Infectious and Inflammatory Diseases, San Diego, CA 92037.ORCID 0000-0001-9323-1649
David Frommhold *Institute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.
Markus Sperandio *Institute of Cardiovascular Physiology and Pathophysiology, Walter Brendel Center of Experimental Medicine, Ludwig-Maximilians-Universität München, PLanegg-Martinsried 82152, Germany.ORCID 0000-0002-7689-3613
Funding
Protein Glycosylation in the Coagulopathy and Inflammation of SepsisP01HL131474 · NHLBI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI MARTH, JAMEY · 2016 to 2025
$26.2MGLYCOSYLTRANSFERASE FUNCTION IN DEVELOPMENT AND DISEASER01DK048247 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JAMEY MARTH · 1994 to 2026
$9.4MProtein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and DiseaseR01AI151371 · NIAID · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI MARTH, JAMEY · 2021 to 2025
$2.4MRegulation of Blood Glycoproteins by Lectin Receptors in Health and DiseaseR01HL158677 · NHLBI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI JAMEY MARTH · 2023 to 2026
$1.9MNHLBI NIH HHS P01 HL131474NHLBI NIH HHS R01 HL158677NIAID NIH HHS R01 AI151371NIDDK NIH HHS R01 DK048247NIH HHS AI151371NIH HHS DK048247NIH HHS HL131474NIH HHS HL158677Wellcome Trust 090063
Abstract
Eosinophil recruitment is a pathological hallmark of many allergic and helminthic diseases. Here, we investigated chemokine receptor CCR3-induced eosinophil recruitment in sialyltransferase
Indexed as
beta-Galactoside alpha-2,3-SialyltransferaseEosinophilsMice, KnockoutReceptors, CCR3SialyltransferasesAnimalsBronchoalveolar Lavage FluidChemokine CCL11MiceMice, Inbred C57BLOvalbuminbeta-Galactoside alpha-2,3-SialyltransferaseCcl11 protein, mouseCcr3 protein, mouseChemokine CCL11OvalbuminReceptors, CCR3Sialyltransferasesasthmachemokineseosinophilinflammationsialylation
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.