SynthesisJMIR public health and surveillance2024
COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis.
Synthesis in JMIR public health and surveillance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Pooled it
- Factors ınfluencing vaccine refusal in children: an umbrella review on COVID-19 and childhood vaccinations.BMC public health · 2026Pooled it
- Willingness to receive mpox vaccine among men who have sex with men: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Parents' and caregivers' views on pediatric meningococcal disease and serogroup B vaccination.Human vaccines & immunotherapeutics · 2026Article
- The Relationship Between COVID-19 Vaccine Regret, Distrust of the Healthcare System, and Future Vaccine Intentions.Journal of evaluation in clinical practice · 2026Article
- Psychosocial and Social Security Risks Linked to Vaccine Misinformation in Romania: Implications for Vaccination Acceptance and Public Policy.Behavioral sciences (Basel, Switzerland) · 2026Article
- COVID-19 vaccine acceptance and recommendation among health workers in nine countries: a pooled analysis of survey data from 2023 to 2024.BMJ global health · 2026Article
- Vaccination Strategies Against Respiratory Pathogens in the Adult Population: A Narrative Review.Vaccines · 2026Review
- The COVID-19 pandemic in the eyes of Polish and Slovak medical students.Frontiers in public health · 2026Article
- Geospatial disparities in post-pandemic SARS-CoV-2 vaccination: Evidence from Chile beyond the national success.PLOS global public health · 2026Article
- From emergence to amplification: an analysis of lifecycle models to address health mis-disinformation in the digital environment.Frontiers in medicine · 2026Review
- From fragmented to integrated surveillance in LMICs: digital pathways for outbreak detection and vaccine intelligence.Frontiers in public health · 2026Review
- Training the public health workforce for generative AI: validation of the Italian Chatbot Usability Questionnaire.Frontiers in public health · 2026Article
- Impf-Guides - experiences with a project aimed at increasing vaccination willingness in Munich during the COVID-19 pandemic.GMS journal for medical education · 2026Article
- Article
- Long-term effectiveness of COVID-19 vaccination in preventing hospitalization among household contacts: A case-control study from December 2021 to April 2023.Human vaccines & immunotherapeutics · 2025Article
- Acceptance and attitudes towards COVID-19 vaccination during pregnancy in Canada.Human vaccines & immunotherapeutics · 2025Article
- Psychological distress and COVID-19 vaccine hesitancy among parents of in-school children after the end of the zero-COVID-19 policy: A city-wide survey in South China.Human vaccines & immunotherapeutics · 2025Article
- The relationships among psychosocial impact, professional type, and vaccine hesitancy among healthcare workers during the COVID-19 pandemic.BMC psychology · 2025Article
- Vaccine Effectiveness in SARS-CoV-2-Infected Pregnant Women with Gestational Diabetes Mellitus: Results from a Multicenter Registry-Based Prospective Cohort Study in Germany.Geburtshilfe und Frauenheilkunde · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
19 authors at 15 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe unprecedented emergence of the COVID-19 pandemic necessitated the development and global distribution of vaccines, making the understanding of global vaccine acceptance and hesitancy crucial to overcoming barriers to vaccination and achieving widespread immunization.
objectiveThis umbrella review synthesizes findings from systematic reviews and meta-analyses to provide insights into global perceptions on COVID-19 vaccine acceptance and hesitancy across diverse populations and regions.
methodsWe conducted a literature search across major databases to identify systematic reviews and meta-analysis that reported COVID-19 vaccine acceptance and hesitancy. The AMSTAR-2 (A Measurement Tool to Assess Systematic Reviews) criteria were used to assess the methodological quality of included systematic reviews. Meta-analysis was performed using STATA 17 with a random effect model. The data synthesis is presented in a table format and via a narrative.
resultsOur inclusion criteria were met by 78 meta-analyses published between 2021 and 2023. Our analysis revealed a moderate vaccine acceptance rate of 63% (95% CI 0.60%-0.67%) in the general population, with significant heterogeneity (I
conclusionsThis review revealed the presence of vaccine hesitancy globally, emphasizing the necessity for population-specific, culturally sensitive interventions and clear, credible information dissemination to foster vaccine acceptance. The observed disparities accentuate the need for continuous research to understand evolving vaccine perceptions and to address the unique concerns and needs of diverse populations, thereby aiding in the formulation of effective and inclusive vaccination strategies.
trial registrationPROSPERO CRD42023468363; https://tinyurl.com/2p9kv9cr.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.