ArticleJournal of psychiatry & neuroscience : JPN
Disproportionate neuroanatomical effects of
Open access · diamondAbstract read
In one paragraph
Article in Journal of psychiatry & neuroscience : JPN. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 3 countries.
Daniel HoopsFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Yohan YeeFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Christopher HammillFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Sammi WongFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Colleen ManittFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Barry J BedellFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Lindsay CahillFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Jason P LerchFrom the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores).
Cecilia Flores *From the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores) cecilia.flores@mcgill.ca john.sled@sickkids.ca.
John G Sled *From the Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ont. (Hoops, Yee, Hammill, Wong, Lerch, Sled); the Department of Medical Biophysics, University of Toronto, Ont. (Hoops, Yee, Lerch, Sled); the Department of Psychiatry, McGill University, Montréal, Que. (Hoops, Flores); the Douglas Mental Health University Institute, Montréal, Que. (Hoops, Manitt, Flores); the Department of Chemistry, Memorial University, St. John's, N.L. (Hoops, Cahill); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Bedell, Flores); the Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neuroscience, University of Oxford, U.K. (Lerch); the Ludmer Centre for Neuroinformatics & Mental Health, McGill University, Montréal, Que. (Flores) cecilia.flores@mcgill.ca john.sled@sickkids.ca.
University of Toronto · CAMemorial University of Newfoundland · CA
Funding
Amphetamine in adolescence disrupts frontal cortex developmentR01DA037911 · NIDA · MCGILL UNIVERSITY · PI FLORES, CECILIA · 2015 to 2024
$2.5MCIHRNIDA NIH HHS R01 DA037911
Abstract
backgroundCritical adolescent neural refinement is controlled by the DCC (deleted in colorectal cancer) protein, a receptor for the netrin-1 guidance cue. We sought to describe the effects of reduced
methodsWe examined neuronal connectivity, structural covariance, and molecular processes in a
resultsWe included 11 LIMITATIONS: Our study involved a single sex (males) at only 2 ages.
conclusionThe neuroanatomical phenotype of
Indexed as
BrainDCC ReceptorDopamineHaploinsufficiencyAge FactorsAgingAnimalsFemaleGene ExpressionMaleMiceMice, Inbred C57BLNeural PathwaysDcc protein, mouseDCC ReceptorDopamine
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.