ArticleNature2024
Multimodal decoding of human liver regeneration.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
33.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 91 citations in OpenAlex.
- A human single-cell atlas identifies OLR1Nature genetics · 2026Article
- mTORC1-TFEB/TFE3 signaling is associated with bile acid diversification during hepatic metabolic adaptation.Science advances · 2026Article
- Hepassocin prevents age-related liver senescence and facilitates liver regeneration by activating AMPK.Signal transduction and targeted therapy · 2026Article
- Solute Carrier Family 1 Member 5 (SLC1A5)-dependent glutamine transport regulates macrophage senescence and efferocytosis during liver regeneration.Molecular biomedicine · 2026Article
- Matrix stiffness shapes early transcriptional trajectories during hepatic stellate cell activation.Hepatology international · 2026Article
- From Collapse to Active Self-Repair: Integrative Multi-Omics and Machine Learning Analysis Map the Hepatic Metabolic Adaption in Response to Simulated Spaceflight Stress.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Succinic acid inhibits hepatocyte regenerative signaling via STAT3 SH2-domain engagement.Molecular biomedicine · 2026Article
- Leveraging IGF signaling to improve the spatial organization and regenerative potential of iPSC-derived vascularized liver organoids.Science advances · 2026Article
- Are we ready for a molecular diagnostics-driven era in hepatobiliary surgery?Hepatobiliary surgery and nutrition · 2026Article
- Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse.Nature biotechnology · 2026Article
- Unleashing innovative cross-organ fibrosis therapies by harnessing the omics revolution.JCI insight · 2026Review
- Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review).International journal of molecular medicine · 2026Review
- Emerging Serological Biomarkers for Autoimmune Hepatitis.Journal of clinical medicine · 2026Review
- Spatial transcriptome mapping identifiesScience advances · 2026Article
- Glutathione peroxidase 3 preserves hepatocyte mitochondrial quality control to enhance macrophage pro-regenerative phenotype during liver regeneration.Clinical and translational medicine · 2026Article
- Single-cell transcriptomics reveals a differential response of human bronchial epithelial cell-types to cadmium chloride.Archives of toxicology · 2026Article
- Immunoglobulin κ drives liver regeneration by stabilizing MYLK to maintain cytoskeletal integrity and promote hepatocyte proliferation.Journal of translational internal medicine · 2026Article
- Esculetin Improves LPS/D-GalN Induced Acute Liver Injury Through AMPK/SIRT1/PGC-1α Signaling Pathway.Antioxidants (Basel, Switzerland) · 2026Article
- The Use of Single-Cell Mitochondrial DNA SNP Combinations for Distinguishing Organ-Specific Cell Types.Cells · 2026Article
- Review
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
36 authors at 12 institutions in 4 countries.
K P MatchettCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
J R Wilson-Kanamori *Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-1372-9912
J R Portman *Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
C A Kapourani *Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-2303-1953
F FercoqCancer Research UK Beatson Institute, Glasgow, UK.ORCID 0000-0002-4825-024X
S MayCancer Research UK Beatson Institute, Glasgow, UK.ORCID 0000-0003-0095-7403
E ZajdelCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
M BeltranCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-8321-2479
E F SutherlandCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
J B G MackeyCancer Research UK Beatson Institute, Glasgow, UK.
M BriceCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-0135-915X
G C WilsonCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
S J WallaceCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-1826-0551
L KittoCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
N T YoungerCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
R DobieCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.
D J MoleCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-6884-7302
G C OniscuEdinburgh Transplant Centre, Royal Infirmary of Edinburgh, Edinburgh, UK.ORCID 0000-0003-1714-920X
S J WigmoreCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-3614-8002
P RamachandranCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-5996-2413
C A VallejosMRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-3638-1960
N O CarragherCancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
M M SaeidinejadInstitute for Liver and Digestive Health, University College London, London, UK.ORCID 0000-0002-1724-4496
A QuagliaDepartment of Cellular Pathology, Royal Free London NHS Foundation Trust, London, UK.
R JalanInstitute for Liver and Digestive Health, University College London, London, UK.ORCID 0000-0002-7747-4015
K J SimpsonDepartment of Hepatology, University of Edinburgh and Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
T J KendallCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-4174-2786
J A RuleDepartment of Internal Medicine, University of Texas, Southwestern Medical Center, Dallas, TX, USA.
W M LeeDepartment of Internal Medicine, University of Texas, Southwestern Medical Center, Dallas, TX, USA.
M HoareEarly Cancer Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0001-5990-9604
C J WestonNIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK.ORCID 0000-0002-9651-1264
J C MarioniCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
S A TeichmannEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Cambridge, UK.ORCID 0000-0002-6294-6366
T G BirdCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-6120-1581
L M CarlinCancer Research UK Beatson Institute, Glasgow, UK.ORCID 0000-0001-7172-5234
N C HendersonCentre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK. Neil.Henderson@ed.ac.uk.ORCID 0000-0002-2273-4094
Centre for Inflammation Research · GBCancer Research UK Scotland Institute · GBEdinburgh Royal Infirmary · GBEuropean Bioinformatics Institute · GBThe University of Texas Southwestern Medical Center · USEdinburgh Cancer Research · GBEuropean Foundation for the Study of Chronic Liver Failure · ESRoyal Free London NHS Foundation Trust · GBThe Alan Turing Institute · GBUniversity College London · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity of Cambridge · GB
Funding
Medical Research Council MR/N008340/1Medical Research Council MR/W015919/1Wellcome Trust
Abstract
The liver has a unique ability to regenerate
Indexed as
Liver Failure, AcuteLiver RegenerationAcetaminophenAnimalsAnnexin A2Cell LineageCell MovementCell ProliferationChemical and Drug Induced Liver InjuryDisease Models, AnimalFemaleHepatocyte Growth FactorHepatocytesHumansLiverMaleAcetaminophenAnnexin A2Anxa2 protein, mouseHepatocyte Growth Factor
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.