Evidence map›Paper›PMID 38693496›Full record

ArticleBMC emergency medicine2024

Diastolic/systolic blood pressure ratio for predicting febrile children with sepsis and progress to septic shock in the emergency department.

Chun-Ting Mu, Ying-Jui Lin, Chih-Ho Chen, Shao-Hsuan Hsia, Jainn-Jim Lin, Oi-Wa Chan, Chen-Wei Yen, Chun-Che Chiu, Han-Pi Chang, Ya-Ting Su and 1 more

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Article in BMC emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Chun-Ting MuChang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
Ying-Jui LinDepartment of Pediatrics, Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Taiwan.
Chih-Ho ChenDepartment of Pediatrics, Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung, Taiwan.
Shao-Hsuan HsiaCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Jainn-Jim LinCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Oi-Wa ChanCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chen-Wei YenCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chun-Che ChiuCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Han-Pi ChangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ya-Ting SuCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
En-Pei LeeCollege of Medicine, Chang Gung University, Taoyuan, Taiwan. pilichrislnp@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGiven the scarcity of studies analyzing the clinical predictors of pediatric septic cases that would progress to septic shock, this study aimed to determine strong predictors for pediatric emergency department (PED) patients with sepsis at risk for septic shock and mortality.

methodsWe conducted chart reviews of patients with ≥ 2 age-adjusted quick Sequential Organ Failure Assessment score (qSOFA) criteria to recognize patients with an infectious disease in two tertiary PEDs between January 1, 2021, and April 30, 2022. The age range of included patients was 1 month to 18 years. The primary outcome was development of septic shock within 48 h of PED attendance. The secondary outcome was sepsis-related 28-day mortality. Initial important variables in the PED and hemodynamics with the highest and lowest values during the first 24 h of admission were also analyzed.

resultsOverall, 417 patients were admitted because of sepsis and met the eligibility criteria for the study. Forty-nine cases progressed to septic shock within 48 h after admission and 368 were discharged without progression. General demographics, laboratory data, and hemodynamics were analyzed by multivariate analysis. Only the minimum diastolic blood pressure/systolic blood pressure ratio (D/S ratio) during the first 24 h after admission remained as an independent predictor of progression to septic shock and 28-day mortality. The best cutoff values of the D/S ratio for predicting septic shock and 28-day mortality were 0.52 and 0.47, respectively.

conclusionsThe D/S ratio is a practical bedside scoring system in the PED and had good discriminative ability in predicting the progression of septic shock and in-hospital mortality in PED patients. Further validation is essential in other settings.

Indexed as

Blood PressureEmergency Service, HospitalSepsisShock, SepticAdolescentChildChild, PreschoolDisease ProgressionFemaleFeverHospital MortalityHumansInfantMaleOrgan Dysfunction ScoresRetrospective StudiesChildrenEmergency department settingHemodynamicsMortalityPredictorsProgressionSepsisSeptic shockShock

Identifiers

PMID38693496
PMCPMC11064385

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