Evidence map›Paper›PMID 38694540›Full record

ReviewDEN open2025

Endoscopic assessment of the J pouch in ulcerative colitis: A narrative review.

Shintaro Akiyama, Edward L Barnes, Tsubasa Onoda, Naoki Ishikawa, Mamiko Shiroyama, Yuka Ito, David T Rubin, Kiichiro Tsuchiya

Open access · goldAbstract readReview
In one paragraph

Review in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Shintaro AkiyamaDepartment of Gastroenterology Institute of Medicine University of Tsukuba Tsukuba Ibaraki Japan.ORCID https://orcid.org/0000-0003-0727-7638
Edward L BarnesDivision of Gastroenterology and Hepatology University of North Carolina at Chapel Hill Chapel Hill USA.
Tsubasa OnodaDepartment of Gastroenterology NHO Mito Medical Center Ibaraki Japan.
Naoki IshikawaDepartment of Gastroenterology Institute of Medicine University of Tsukuba Tsukuba Ibaraki Japan.
Mamiko ShiroyamaDepartment of Gastroenterology Institute of Medicine University of Tsukuba Tsukuba Ibaraki Japan.
Yuka ItoDepartment of Gastroenterology NHO Mito Medical Center Ibaraki Japan.
David T RubinUniversity of Chicago Medicine Inflammatory Bowel Disease Center Chicago USA.
Kiichiro TsuchiyaDepartment of Gastroenterology Institute of Medicine University of Tsukuba Tsukuba Ibaraki Japan.
University of Tsukuba · JPNational Hospital Organization Mito Medical Center · JPUniversity of Chicago · USUniversity of North Carolina at Chapel Hill · US

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 1990 to 2025
$29.8M
Probing short and long term consequences of Small and Large Bowel Microbiota Transplants on Host Physiology: Implications for the development of future live biotherapeuticsR01DK138072 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG, Kristina Brooke Martinez-Guryn · 2024 to 2026
$2.1M
NIDDK NIH HHS P30 DK042086NIDDK NIH HHS R01 DK138072
6 · The paper itself

Abstract

Patients with ulcerative colitis sometimes need a total colectomy with ileal pouch-anal anastomosis due to medically refractory disease or colitis-associated neoplasia. Up to 50% of patients with ulcerative colitis postoperatively develop pouchitis and the rate of chronic inflammatory pouch conditions requiring pouch excision or diverting ileostomy is reported to be 10%. In order to diagnose and monitor pouchitis, pouchoscopy is essential to assess endoscopic inflammatory findings of the J pouch and to survey neoplasia development, particularly in the remnant distal rectum. However, endoscopic protocols for the evaluation of the pouch may not be standardized worldwide and the reliability of existing disease activity indices for pouchitis has been questioned due to the lack of validation. Recently, reliable endoscopic scoring systems based on an observation of the anatomical location of the J pouch were reported and a significant association between the distribution pattern of endoscopic inflammation (i.e., endoscopic phenotype) and pouch outcomes was also uncovered. In this review, we discuss how to survey the J pouch using pouchoscopy, endoscopic indices for pouchitis disease activity, endoscopic phenotypes and classification, and the pathological mechanisms of pouchitis phenotype in patients with ulcerative colitis.

Indexed as

endoscopygoblet cellsphenotypepouchitisulcerative colitis

Identifiers

PMID38694540
PMCPMC11058686
OpenAlexW4396519143

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.