Evidence map›Paper›PMID 38695960›Full record

ReviewEJNMMI radiopharmacy and chemistry2024

Alessandra Boschi, Luca Urso, Licia Uccelli, Petra Martini, Luca Filippi

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in EJNMMI radiopharmacy and chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06753513 (Clinical Application of 99mTc-FDPH46 SPECT/CT Imaging in Malignant Solid Tumor), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06753513 not yet recruitingnot on this map

Clinical Application of 99mTc-FDPH46 SPECT/CT Imaging in Malignant Solid Tumor: a Prospective Exploratory Study

TypeobservationalSponsorZhejiang UniversityRan2024 to 2026Enrolled20ConditionsMalignant Tumors, Solid Tumor MalignancyArms99mTc-FDPH46 SPECT/CT Imaging
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Comparative Evaluation of [Molecular imaging and biology · 2026
    Article
  2. [Scientific reports · 2026
    Article
  3. Review
  4. Quantitative imaging in medicine and surgery · 2026
    Article
  5. Article
  6. Review
  7. Single Photon Emission Computed Tomography Tracer.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Alessandra Boschi *Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Via L. Borsari, 46, 44121, Ferrara, Italy.
Luca Urso *Department of Translational Medicine, University of Ferrara, Via Fossato di Mortara, 70 c/o viale Eliporto, 44121, Ferrara, Italy.
Licia UccelliDepartment of Translational Medicine, University of Ferrara, Via Fossato di Mortara, 70 c/o viale Eliporto, 44121, Ferrara, Italy. ccl@unife.it.ORCID http://orcid.org/0000-0002-1490-0718
Petra MartiniDepartment of Environmental and Prevention Sciences, University of Ferrara, Via L. Borsari, 46 44121, Ferrara, Italy. petra.martini@unife.it.
Luca FilippiNuclear Medicine Unit, Department of Oncohaematology, Fondazione PTV Policlinico Tor Vergata University Hospital, Rome, Italy.
University of Ferrara · ITPoliclinico Tor Vergata · IT

Funding

Università degli Studi di Ferrara FAR2020
6 · The paper itself

Abstract

backgroundIn recent years, fibroblast activating protein (FAP), a biomarker overexpressed by cancer-associated fibroblasts, has emerged as one of the most promising biomarkers in oncology. Similarly, FAP overexpression has been detected in various fibroblast-mediated inflammatory conditions such as liver cirrhosis and idiopathic pulmonary fibrosis. Along this trajectory, FAP-targeted positron emission tomography (PET), utilizing FAP inhibitors (FAPi) labeled with positron emitters, has gained traction as a powerful imaging approach in both cancer and inflammation. However, PET represents a high-cost technology, and its widespread adoption is still limited compared to the availability of gamma cameras. To address this issue, several efforts have been made to explore the potential of [ MAIN BODY: Several approaches have been investigated for labeling FAPi-based compounds with

conclusionsThis overview focuses on the various radiochemical strategies for obtaining [

Indexed as

Fibroblast activation proteinInflammationMolecular imagingOncologyPETSPECT

Identifiers

PMID38695960
PMCPMC11065808
OpenAlexW4396578966

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.