Evidence map›Paper›PMID 38696255›Full record

ArticleMolecular biology of the cell2024

Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane.

Caroline Q Connors, Michael S Mauro, J Tristian Wiles, Andrew D Countryman, Sophia L Martin, Benjamin Lacroix, Mimi Shirasu-Hiza, Julien Dumont, Karen E Kasza, Timothy R Davies and 1 more

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Caroline Q ConnorsDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.
Michael S MauroDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0001-7013-6139
J Tristian WilesDepartment of Biological Sciences, Columbia University, New York, NY 10027.
Andrew D CountrymanDepartment of Biomedical Engineering, Columbia University, New York, NY 10027.
Sophia L MartinDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.
Benjamin LacroixUniversité Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France.
Mimi Shirasu-HizaDepartment of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032.
Julien DumontUniversité Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France.
Karen E KaszaDepartment of Mechanical Engineering, Columbia University, New York, NY 10027.
Timothy R DaviesDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.
Julie C CanmanDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0001-8135-2072

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Circadian-Regulated Aging PhysiologiesR01AG045842 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michele M Shirasu-Hiza · 2013 to 2026
$5.1M
Circadian regulation of physiological functionsR35GM127049 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michele M Shirasu-Hiza · 2018 to 2026
$3.9M
Cell type-variation of cytokinesisR01GM117407 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2016 to 2023
$2.9M
Mechanisms coordinating cell behaviors within tissues during developmentR35GM138380 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Karen Kasza · 2020 to 2026
$2.8M
NIA NIH HHS R01 AG045842NIGMS NIH HHS R01 GM117407NIGMS NIH HHS R35 GM127049NIGMS NIH HHS R35 GM138380NIH HHS P40 OD010440
6 · The paper itself

Abstract

Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an actomyosin contractile ring at the division plane. The mechanisms underlying cell type-specific differences in cytokinesis remain unknown. Germ cells are totipotent cells that pass genetic information to the next generation. Previously, using

Indexed as

ActinsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell DivisionCytokinesisGerm CellsSeptinsActomyosinAnimalsContractile ProteinsActinsActomyosinanillinCaenorhabditis elegans ProteinsContractile ProteinsSeptins

Identifiers

PMID38696255
PMCPMC11244169

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.