Evidence map›Paper›PMID 38698309›Full record

Observational studyBMC pregnancy and childbirth2024

Prematurity and congenital malformations differ according to the type of pregestational diabetes.

Monica Ballesteros, A Guarque, M Ingles, N Vilanova, M Lopez, L Martin, M Jane, L Puerto, M Martinez, M De la Flor and 2 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Monica Ballesteros *Department of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain. mballesteros.hj23.ics@gencat.cat.
A GuarqueDepartment of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
M InglesCIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Carlos III Health Institute, Madrid, Spain.
N VilanovaInstitut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.
M LopezDepartment of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
L MartinDepartment of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
M JaneDepartment of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
L PuertoDepartment of Obstetrics and Gynecology, University Hospital of Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.
M MartinezDepartment of Obstetrics and Gynecology, University Hospital of Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.
M De la FlorDepartment of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
J VendrellDepartment of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
A Megia *Department of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.

Funding

Instituto de Salud Carlos III PI21/1479
6 · The paper itself

Abstract

backgroundDiabetes mellitus (DM) is the most common metabolic disorder in pregnancy. Women with Type 2 DM seems to have no better perinatal outcomes than those with Type 1 DM.

methodsSingle-center prospective cohort observational study. Pregnant women with diabetes (141 with Type 1 DM and 124 with Type 2 DM) that were followed in the university hospital between 2009 and 2021 were included in this study. Clinical data and obstetric and perinatal outcomes were collected.

resultsAs expected, women with Type 1 DM were younger and had a longer duration of diabetes than women with Type 2 DM. Obesity and chronic hypertension were higher in the group of women with Type 2 DM and their value of HbA1c in the second and third trimesters were lower than in Type 1 DM. No differences in prematurity were found, but more extreme prematurity was observed in Type 2 DM, as well as a higher rate of congenital malformations. The frequency of hypoglycemia and the weight of the newborn was higher in Type 1 DM. The maternal independent factors related to the weight of the newborn were: the glycemic control at the third trimester, the weight gain during pregnancy, and pregestational BMI.

conclusionsNewborns born to mothers with Type 1 DM were larger and had a higher frequency of hypoglycemia, while congenital malformations and precocious preterm was more associated to Type 2 DM. Metabolic control, weight gain and pregestational weight were important determinants of both obstetric and neonatal complications.

Indexed as

Congenital AbnormalitiesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Pregnancy in DiabeticsPremature BirthAdultBirth WeightBody Mass IndexFemaleGlycated HemoglobinHumansHypoglycemiaInfant, NewbornPregnancyPregnancy OutcomeProspective StudiesGlycated HemoglobinDiabetesHigh-risk pregnancyMaternal-fetal medicineObesityPregnancyPreterm delivery

Identifiers

PMID38698309
PMCPMC11064320

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.