Evidence map›Paper›PMID 38698992›Full record

ArticleHeliyon2024

Octopaminergic descending neurons in

Helene Babski, Marcello Codianni, Vikas Bhandawat

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Octopamine receptors inFrontiers in molecular neuroscience · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Helene BabskiSchool of Biomedical Engineering and Health Sciences, Drexel University, USA.
Marcello CodianniSchool of Biomedical Engineering and Health Sciences, Drexel University, USA.
Vikas BhandawatSchool of Biomedical Engineering and Health Sciences, Drexel University, USA.

Funding

The Circuit Logic of Modulation of Locomotion by OdorsR01DC015827 · NIDCD · DUKE UNIVERSITY · PI Vikas Bhandawat · 2017 to 2026
$2.5M
Understanding the Role of Descending Neuromodulation in Flexible Control of BehaviorR01NS097881 · NINDS · DUKE UNIVERSITY · PI BHANDAWAT, VIKAS · 2017 to 2021
$1.7M
NIDCD NIH HHS R01 DC015827NINDS NIH HHS R01 NS097881
6 · The paper itself

Abstract

Projection neurons that communicate between different brain regions and local neurons that shape computation within a brain region form the majority of all neurons in the brain. Another important class of neurons is neuromodulatory neurons; these neurons are in much smaller numbers than projection/local neurons but have a large influence on computations in the brain. Neuromodulatory neurons are classified by the neurotransmitters they carry, such as dopamine and serotonin. Much of our knowledge of the effect of neuromodulators comes from experiments in which either a large population of neuromodulatory neurons or the entire population is perturbed. Alternatively, a given neuromodulator is exogenously applied. While these experiments are informative of the general role of the neurotransmitter, one limitation of these experiments is that the role of individual neuromodulatory neurons remains unknown. In this study, we investigate the role of a class of octopaminergic (octopamine is the invertebrate equivalent of norepinephrine) neurons in

Identifiers

PMID38698992
PMCPMC11064449

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.