Evidence map›Paper›PMID 38700136›Full record

ArticleeLife2024

Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex.

Hao Li, Jingyu Feng, Mengying Chen, Min Xin, Xi Chen, Wenhao Liu, Liping Wang, Kuan Hong Wang, Jufang He

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. mGluR5 in ECAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Dietary Fenbendazole Treatment Does Not Impair Skilled Forelimb Motor Function in C57BL/6J Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao LiDepartments of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0001-5933-1443
Jingyu FengDepartments of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Mengying ChenDepartments of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Min XinDepartments of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Xi ChenDepartments of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-2144-6584
Wenhao LiuDepartments of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
Liping WangThe Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Kuan Hong WangDepartment of Neuroscience, Del Monte Institute for Neuroscience, University of Rochester Medical Center, Rochester, United States.ORCID https://orcid.org/0000-0002-2249-5417
Jufang HeDepartments of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-4288-5957

Funding

Health and Medical Research Fund HMRF09203656Hong Kong Research Grants Council GRF11101521MHong Kong Research Grants Council GRF11103220MHong Kong Research Grants Council, Collaborative Research Fund C1043-21GFInnovation and Technology Fund GHP_075_19GDInnovation and Technology Fund MRP/053/18XNational Natural Science Foundation of China NSFC31671102
6 · The paper itself

Abstract

Cholecystokinin (CCK) is an essential modulator for neuroplasticity in sensory and emotional domains. Here, we investigated the role of CCK in motor learning using a single pellet reaching task in mice. Mice with a knockout of

Indexed as

CholecystokininLearningMice, KnockoutMotor CortexMotor SkillsNeuronal PlasticityAnimalsMaleMiceReceptor-Interacting Protein Serine-Threonine Kinase 2CholecystokininReceptor-Interacting Protein Serine-Threonine Kinase 2Ripk2 protein, mousecholecystokininentorhinal cortexmotor cortexmotor skill learningmouseneurosciencesingle pellet reaching task

Identifiers

PMID38700136
PMCPMC11068356

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.