Evidence mapPaperPMID 38708204Full record

ArticleACS omega2024

Sustained Release Studies of Metformin Hydrochloride Drug Using Conducting Polymer/Gelatin-Based Composite Hydrogels.

Aleena Mir, Wilbert J Fletcher, Darlene K Taylor, Javed Alam, Ufana Riaz

Abstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aleena MirMaterials Research Laboratory, Department of Chemistry, Jamia Millia Islamia, New Delhi 110025, India.ORCID https://orcid.org/0000-0002-8402-4469
Wilbert J FletcherDepartment of Chemistry and Biochemistry, North Carolina Central University, Durham, North Carolina 27707, United States.
Darlene K TaylorDepartment of Chemistry and Biochemistry, North Carolina Central University, Durham, North Carolina 27707, United States.
Javed AlamKing Abdullah Institute for Nanotechnology (KAIN), King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Ufana RiazDepartment of Chemistry and Biochemistry, North Carolina Central University, Durham, North Carolina 27707, United States.ORCID https://orcid.org/0000-0001-7485-4103

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work highlights the synthesis and characterization of conducting polymer (CP)-based composite hydrogels with gelatin (GL-B) for their application as drug delivery vehicles. The spectral, morphological, and rheological properties of the synthesized hydrogels were explored, and morphological studies confirmed formation of an intense interpenetrating network. Rheological measurements showed variation in the flow behavior with the type of conducting polymer. The hydrogels showed a slow drug release rate of about 10 h due to the presence of the conducting polymer. The release kinetics were fitted in various mathematical models and were best fit in first order for PNA-, POPD-, and PANI-based GL-B hydrogels, and the PVDF/GL-B hydrogel was best fit in the zero-order models. The drug release was found to follow the order: POPD/GL-B > PANI/GL-B > PVDF/GL-B.

Identifiers

PMID38708204
PMCPMC11064195

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.