Evidence map›Paper›PMID 38712094›Full record

ArticlebioRxiv : the preprint server for biology2024

Hair follicles modulate skin barrier function.

Noah C Ford, Rachel E Benedeck, Matthew T Mattoon, Jamie K Peterson, Arlee L Mesler, Natalia A Veniaminova, Danielle J Gardon, Shih-Ying Tsai, Yoshikazu Uchida, Sunny Y Wong

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Noah C FordDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Rachel E BenedeckDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Matthew T MattoonDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Jamie K PetersonDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Arlee L MeslerDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Natalia A VeniaminovaDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Danielle J GardonDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Shih-Ying TsaiDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Yoshikazu UchidaDepartment of Food Science and Nutrition, and Convergence Program of Material Science for Medicine and Pharmaceutics, Hallym University, Chuncheon, Republic of Korea.
Sunny Y WongDepartment of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-0222-2681

Funding

University of Michigan Skin Biology and Diseases Resource-based CenterP30AR075043 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Johann Eli Gudjonsson · 2019 to 2026
$6.6M
The Hair Follicle Infundibulum: A Potential Mediator of Skin Barrier FunctionR01AR065409 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sunny Y Wong · 2014 to 2026
$3.8M
Exploring hair follicle-associated functions in normal and ichthyotic skinR01AR080654 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sunny Y Wong · 2022 to 2026
$2.0M
NIAMS NIH HHS P30 AR075043NIAMS NIH HHS R01 AR065409NIAMS NIH HHS R01 AR080654
6 · The paper itself

Abstract

Our skin provides a protective barrier that shields us from our environment. Barrier function is typically associated with interfollicular epidermis; however, whether hair follicles influence this process remains unclear. Here, we utilize a potent genetic tool to probe barrier function by conditionally ablating a quintessential epidermal barrier gene,

Identifiers

PMID38712094
PMCPMC11071379

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.