Evidence map›Paper›PMID 38713090›Full record

ReviewPhysiology (Bethesda, Md.)2024

Mitochondrial Calcium Regulation of Cardiac Metabolism in Health and Disease.

Enrique Balderas, Sandra H J Lee, Neeraj K Rai, David M Mollinedo, Hannah E Duron, Dipayan Chaudhuri

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Mitochondrial Calcium Signaling in Hepatocyte Health and Disease.Cold Spring Harbor perspectives in biology · 2026
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Peroxynitrite regulates ER stress-mediated CaJournal of translational medicine · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Mitochondrial Calcium Uniporter-Mediated Regulation of the SIRT3/GSK3β/β-Catenin Signaling Pathway in Vascular Remodeling.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  17. Article
  18. MICU proteins facilitate CaResearch square · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Enrique BalderasNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States.ORCID 0000-0001-8780-9272
Sandra H J LeeNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States.
Neeraj K RaiNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States.
David M MollinedoNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States.
Hannah E DuronNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States.
Dipayan ChaudhuriNora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States.ORCID 0000-0003-0605-7334

Funding

Metabolic Impact and Mechanism of Enhanced Mitochondrial Calcium Uptake in Mitochondrial CardiomyopathiesR01HL141353 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Dipayan Chaudhuri · 2018 to 2026
$4.3M
Regulation of the mitochondrial calcium uniporterR01HL165797 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Dipayan Chaudhuri · 2022 to 2026
$2.5M
Structural basis for mitochondrial calcium uniporter functionR00HL124070 · NHLBI · UNIVERSITY OF UTAH · PI CHAUDHURI, DIPAYAN · 2016 to 2018
$747k
Structural basis for mitochondrial calcium uniporter functionK99HL124070 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI CHAUDHURI, DIPAYAN · 2014 to 2015
$292k
A novel mechanism of mitochondrial protein turnover in Complex I deficient mitochondrial cardiomyopathyF30HL165806 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI CVRTI, SANDRA HYUNJOO · 2022 to 2025
$169k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) F30HL165806HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL124070HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL141353NHLBI NIH HHS F30 HL165806NHLBI NIH HHS K99 HL124070NHLBI NIH HHS R00 HL124070NHLBI NIH HHS R01 HL141353NHLBI NIH HHS R01 HL165797Nora Eccles Treadwell Foundation
6 · The paper itself

Abstract

Oxidative phosphorylation is regulated by mitochondrial calcium (Ca

Indexed as

CalciumMitochondria, HeartAnimalsHeart DiseasesHumansMyocardiumOxidative PhosphorylationReactive Oxygen SpeciesCalciumReactive Oxygen Speciesheart failureischemia-reperfusion injuryMCUmitochondrial calcium transportmitochondrial cardiomyopathy

Identifiers

PMID38713090
PMCPMC11460536

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.