Trial reportNature medicine2024
Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial.
Trial report in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Generative AI in Precision Nutrition: A Review of Current Developments and Future Directions.Nutrients · 2026Pooled it
- Impact of exercise-based prehabilitation on cardiometabolic health in surgical patients with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Health-related quality of life, compliance and sustained adherence on a low-carbohydrate high-fat diet compared with a high-carbohydrate low-fat diet in people with type 2 diabetes.The American journal of clinical nutrition · 2026Trial
- Gut microbiome predicts personalized responses to dietary fiber in prediabetes: a randomized, open-label trial.Nature communications · 2025Trial
- Baseline Characteristics of Weight-Loss Success in a Personalized Nutrition Intervention: A Secondary Analysis.Nutrients · 2025Trial
- Human-Centered Innovation: Precision Nutrition and the Future of Food.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Postprandial Glucose Spikes in Free-Living Adults With Normoglycaemia Are Associated With Modifiable Dietary and Temporal Factors: A Real-World CGM Study.Diabetes, obesity & metabolism · 2026Article
- Quantifying the Contributions of Food, Glucose, Sleep, and Microbiome Data to Personalized Glycemic Response Prediction.Current developments in nutrition · 2026Article
- 1-Kestose as a Candidate Precision Bioactive Component: From GH32-Dependent Gut Microbiota Regulation to Human Health Enhancement.Foods (Basel, Switzerland) · 2026Review
- Digital determinants of nutrition: the case for a distinct domain to guide health promotion research and policy.Health promotion international · 2026Review
- Fermented food microbiome: influence on oral and gut microbiota, and human health.Nature reviews. Microbiology · 2026Review
- Precision nutrition for the prevention and management of inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2026Review
- An Experiment in Personalized Shopping for Optimal Health, with Integration of Nutrigenetics and Gut Microbiome Information.Nutrients · 2026Article
- Effects of personalized nutrition on cardiometabolic biomarkers in adults with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials.Nutrition & metabolism · 2026Review
- Review
- [Nutrition recommendations for people with diabetes (Update 2026)].Wiener klinische Wochenschrift · 2026Review
- Toward standardized personalized nutrition: a methodological scoping review and meta-analysis of randomized controlled trials in adults with overweight and obesity.Genes & nutrition · 2026Article
- Precision nutrition must consider cost-effectiveness to deliver benefits to patients.Nature medicine · 2026Article
- Computational Nutrition in Practice: Challenges and Opportunities From an Early-Career Perspective.The Journal of nutrition · 2026Article
- The Oral-Gut-Immune-Nutrition Axis in Rheumatoid Arthritis: Molecular Mechanisms and Therapeutic Implications.International journal of molecular sciences · 2026Review
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
Abstract
Large variability exists in people's responses to foods. However, the efficacy of personalized dietary advice for health remains understudied. We compared a personalized dietary program (PDP) versus general advice (control) on cardiometabolic health using a randomized clinical trial. The PDP used food characteristics, individual postprandial glucose and triglyceride (TG) responses to foods, microbiomes and health history, to produce personalized food scores in an 18-week app-based program. The control group received standard care dietary advice (US Department of Agriculture Guidelines for Americans, 2020-2025) using online resources, check-ins, video lessons and a leaflet. Primary outcomes were serum low-density lipoprotein cholesterol and TG concentrations at baseline and at 18 weeks. Participants (n = 347), aged 41-70 years and generally representative of the average US population, were randomized to the PDP (n = 177) or control (n = 170). Intention-to-treat analysis (n = 347) between groups showed significant reduction in TGs (mean difference = -0.13 mmol l
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.