Evidence map›Paper›PMID 38716377›Full record

ArticleInternational journal of genomics2024

A Chromosomal-Level Genome of

Rongxuan Hu, Haifeng Huang, Ying Zhou, Yanshan Liu, Yaning Ren, Yuanfen Liao, Cunyin Yuan, Xiaohong Gu, Yubao Cui

Abstract read
In one paragraph

Article in International journal of genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rongxuan HuDepartment of Rheumatology, The Affiliated Children's Hospital of Jiangnan University, Wuxi 214023, China.ORCID https://orcid.org/0000-0002-0932-5907
Haifeng HuangDermatological Department, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.ORCID https://orcid.org/0009-0009-4189-4657
Ying ZhouDepartment of Pediatrics Laboratory, The Affiliated Children's Hospital of Jiangnan University, Wuxi 214023, China.ORCID https://orcid.org/0000-0003-4406-9870
Yanshan LiuDepartment of Pediatrics Laboratory, The Affiliated Children's Hospital of Jiangnan University, Wuxi 214023, China.ORCID https://orcid.org/0000-0002-2452-0970
Yaning RenClinical Research Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.ORCID https://orcid.org/0009-0006-0921-3987
Yuanfen LiaoClinical Research Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.ORCID https://orcid.org/0009-0001-0907-5995
Cunyin YuanClinical Research Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.ORCID https://orcid.org/0009-0003-3748-1258
Xiaohong GuRespiratory Department, The Affiliated Children's Hospital of Jiangnan University, Wuxi 214023, China.ORCID https://orcid.org/0009-0008-9108-9931
Yubao CuiClinical Research Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.ORCID https://orcid.org/0000-0001-7736-8012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Genome data have been used to find novel allergen from house dust mites. Here, we aim to construct a chromosome-level genome assembly of Methods: We achieved a chromosome-level assembly of Results: A 62.43 Mb genome was assembled with a 0.52% heterozygosity rate and a 36.11 Merqury-estimated quality value. The assembled genome represents 92.1% completeness benchmarking universal single-copy orthologs with a scaffold N50 value of 7.11 Mb. Hi-C scaffolding of the genome resulted in construction of 10 pseudochromosomes. The genome comprises 13.01% (7.66 Mb) repetitive sequences and predicts 10,709 protein-coding genes, 96.57% of which are functionally annotated. Moreover, we identified and located 36 allergen groups on specific chromosomes, including allergens Der f 1, Der f 2, Der f 23, Der f 4, Der f 5, Der f 7, and Der f 21 located on chromosomes 2, 1, 7, 3, 4, 6, and 4, respectively. Conclusion: This comprehensive genomic data provides valuable insights into mite biology and evolutionary adaptations, potentially advancing

Identifiers

PMID38716377
PMCPMC11074847

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.